1-Propanoylpiperidin-4-one

Base Information

Chemical Name:1-Propanoylpiperidin-4-one
CAS No.:91623-91-5
Molecular Formula:C8H13NO2
Molecular Weight:155.19400
Hs Code.:
European Community (EC) Number:827-647-9
Mol file:91623-91-5.mol

Synonyms:1-propanoylpiperidin-4-one;91623-91-5;1-Propionylpiperidin-4-one;SCHEMBL327614;AKOS000193556;AB91947;EN300-52482;G36856;Z33618770

Suppliers and Price of 1-Propanoylpiperidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Propionylpiperidin-4-one
250mg
$ 240.00

American Custom Chemicals Corporation
1-PROPANOYLPIPERIDIN-4-ONE 95.00%
5G
$ 1295.03

American Custom Chemicals Corporation
1-PROPANOYLPIPERIDIN-4-ONE 95.00%
2.5G
$ 1065.66

American Custom Chemicals Corporation
1-PROPANOYLPIPERIDIN-4-ONE 95.00%
1G
$ 765.23

AK Scientific
1-Propanoylpiperidin-4-one
100mg
$ 172.00

Acrotein
1-Propionylpiperidin-4-one 97%
5g
$ 495.00

Acrotein
1-Propionylpiperidin-4-one 97%
0.5g
$ 110.00

ACHEMBLOCK
1-Propionylpiperidin-4-one 95%
5G
$ 605.00

ACHEMBLOCK
1-Propionylpiperidin-4-one 95%
1G
$ 200.00

Total 5 raw suppliers

Chemical Property of 1-Propanoylpiperidin-4-one

Chemical Property:

Boiling Point:237.2±15.0 °C(Predicted)
PKA:-0.72±0.20(Predicted)
PSA：37.38000
Density:1.094±0.06 g/cm3(Predicted)
LogP:0.52580
XLogP3:-0.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:155.094628657
Heavy Atom Count:11
Complexity:167

Purity/Quality:

95-265%min ^*data from raw suppliers

1-Propionylpiperidin-4-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)N1CCC(=O)CC1

Technology Process of 1-Propanoylpiperidin-4-one

There total 1 articles about 1-Propanoylpiperidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 41979-39-9
4-piperidone hydrochloride

: 79-03-8
propionyl chloride

: 91623-91-5
1-propionyl-4-piperidone

Guidance literature:: With potassium carbonate; In chloroform; at 60 ℃;
DOI:10.1016/S0960-894X(03)00437-2

Reference yield: 68.0%

: 100-46-9
benzylamine

: 91623-91-5
1-propionyl-4-piperidone

: 577778-37-1
1-(4-benzylamino-piperidin-1-yl)-propan-1-one

Guidance literature:: With titanium(IV) isopropylate; sodium cyanoborohydride; In ethanol;
DOI:10.1016/S0960-894X(03)00437-2

Reference yield:

: 91623-91-5
1-propionyl-4-piperidone

: 4-fluoro-N-(1-propionyl-piperidin-4-yl)-benzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: 68 percent / (iPrO)4Ti; NaBH₃CN / ethanol

2: 97 percent / HCOONH₄; Pd/C / methanol

3: 82 percent / Et₃N / acetonitrile

With titanium(IV) isopropylate; palladium on activated charcoal; ammonium formate; sodium cyanoborohydride; triethylamine; In methanol; ethanol; acetonitrile;
DOI:10.1016/S0960-894X(03)00437-2