3,3'-Dimethoxy-4,4'-dihydroxybiphenyl

Base Information

• Chemical Name: 3,3'-Dimethoxy-4,4'-dihydroxybiphenyl
• CAS No.: 4433-09-4
• Molecular Formula: C14H14O4
• Molecular Weight: 246.26
• Hs Code.: 2922299090
• Mol file: 4433-09-4.mol

Synonyms:3,3'-dimethoxy-4,4'-biphenol;4.4'-Dioxy-3.3'-dimethoxy-diphenyl;3,3'-Dimethoxy-4,4'-dihydroxy-diphenyl;4,4'-Biguaiacol;3,3'-dimethoxybiphenyl-4,4'-diol;4,4'-Dihydroxy-3,3'-dimethoxybiphenyl;

Chemical Property of 3,3'-Dimethoxy-4,4'-dihydroxybiphenyl

Chemical Property:

• PSA: 58.92000
• LogP: 2.78200

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Use Description: 3,3'-Dimethoxy-4,4'-dihydroxybiphenyl, a chemical compound with specific properties, has various applications across different fields. In the pharmaceutical and medicinal chemistry sectors, it can serve as a valuable synthetic intermediate, contributing to the development of pharmaceuticals and potentially serving as a core structure in the creation of new drugs. Its presence can also be found in the field of organic chemistry, where it may be employed as a reagent or catalyst in various reactions. Furthermore, in academic and research settings, this compound could play a pivotal role in studies exploring the synthesis and characterization of new organic molecules, thereby advancing the understanding of chemical processes. Its versatility and significance in drug development and chemical research underscore its importance in these respective fields.

Technology Process of 3,3'-Dimethoxy-4,4'-dihydroxybiphenyl

There total 5 articles about 3,3'-Dimethoxy-4,4'-dihydroxybiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxy-phenol (90-05-1) → 4,4'-Dihydroxy-3,3'-dimethoxybiphenyl (4433-09-4) + 5,3'-Dimethoxy-biphenyl-3,4,4'-triol (155100-96-2) + 3-(4-hydroxy-3-methoxyphenyl)-5,3'-dimethoxy-4,4'-biphenol

Guidance literature:

With dihydrogen peroxide; peroxidase; at 25 ℃; for 2h;

Reference yield:

2-methoxy-phenol (90-05-1) → 4,4'-Dihydroxy-3,3'-dimethoxybiphenyl (4433-09-4)

Guidance literature:

With sulfuric acid; bei der elektrolytischen Oxydation;

Reference yield:

1-acetoxy-4-iodo-2-methoxy-benzene (179902-22-8) → 4,4'-Dihydroxy-3,3'-dimethoxybiphenyl (4433-09-4)

Guidance literature:

Multi-step reaction with 2 steps

1: Cu / 40 h / 250 °C

2: (saponification)

With copper;

upstream raw materials:

2-methoxy-phenol

4,4'-Diacetoxy-3,3'-dimethoxy-biphenyl

1-acetoxy-4-iodo-2-methoxy-benzene

Downstream raw materials:

3,3'-dimethoxy-4,4'-biphenoquinone

Refernces

• 1、 Kobayashi, Akio,Koguchi, Yutaka,Kanzaki, Hiroshi,Kajiyama, Shin-ichiro,Kawazu, Kazuyoshi. "Production of a New Type of Bioactive Phenolic Compound". . p. 133 - 134. Retrieved 2007/10/02.