O,O-Dimethyl acetylthiophosphoramidate

Base Information

• Chemical Name: O,O-Dimethyl acetylthiophosphoramidate
• CAS No.: 42072-27-5
• Molecular Formula: C4H10 N O3 P S
• Molecular Weight: 183.168
• Hs Code.: 2931900090
• European Community (EC) Number: 255-646-8
• DSSTox Substance ID: DTXSID80885857
• Nikkaji Number: J278.321E
• Wikidata: Q82864553
• Mol file: 42072-27-5.mol

Synonyms:O,O-Dimethyl acetylthiophosphoramidate;42072-27-5;N-dimethoxyphosphinothioylacetamide;EINECS 255-646-8;Phosphoramidothioic acid, acetyl-, O,O-dimethyl ester;Phosphoramidothioic acid, N-acetyl-, O,O-dimethyl ester;SCHEMBL1896334;DTXSID80885857;dimethyl acetylphosphoroamidothioate;Acetylamidothiophosphoric acid O,O-dimethyl ester

Chemical Property of O,O-Dimethyl acetylthiophosphoramidate

Chemical Property:

• Boiling Point: °Cat760mmHg
• PKA: 11.26±0.46(Predicted)
• Flash Point: °C
• PSA: 92.95000
• Density: 1.261g/cm³
• LogP: 2.13070
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 183.01190135
• Heavy Atom Count: 10
• Complexity: 164

Purity/Quality:

98%Min ^*data from raw suppliers

O,O-Dimethylacetylphosphoramidothioate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NP(=S)(OC)OC

Technology Process of O,O-Dimethyl acetylthiophosphoramidate

There total 1 articles about O,O-Dimethyl acetylthiophosphoramidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O,O-dimethyl phosphoramidothioate (17321-47-0) + acetic anhydride (108-24-7) → O,O-dimethyl N-acetylphosphoramidothioate (42072-27-5)

Guidance literature:

With phosphoric acid; at 80 ℃; for 1h;

DOI:10.1021/jf021020i

Reference yield:

O,O-dimethyl N-acetylphosphoramidothioate (42072-27-5) + dimethyl sulfate (77-78-1) → Acephate (30560-19-1)

Guidance literature:

In dichloromethane; Heating;

DOI:10.1080/10426500902797079

upstream raw materials:

O,O-dimethyl phosphoramidothioate

acetic anhydride

Downstream raw materials:

Acephate