Glafenine

Base Information

Chemical Name:Glafenine
CAS No.:3820-67-5
Molecular Formula:C19H17ClN2O4
Molecular Weight:372.808
Hs Code.:2933499090
European Community (EC) Number:223-315-7
NSC Number:757808
UNII:46HL4I09AH
DSSTox Substance ID:DTXSID1048546
Nikkaji Number:J3.409F
Wikipedia:Glafenine
Wikidata:Q5566483
NCI Thesaurus Code:C72119
Metabolomics Workbench ID:52057
ChEMBL ID:CHEMBL146095
Mol file:3820-67-5.mol

Synonyms:Exidol;Glafenin;Glafenine;Glaphenine;Glycerylaminophenaquine

Suppliers and Price of Glafenine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Glafenine
100mg
$ 290.00

Sigma-Aldrich
Glafenine hydrochloride analytical standard
1 g
$ 17.40

Crysdot
Glafenine 98+%
1g
$ 400.00

Chemenu
2,3-dihydroxypropyl2-((7-chloroquinolin-4-yl)amino)benzoate 98%
1g
$ 374.00

Arctom
Glafenine ≥98%
250mg
$ 29.00

Arctom
Glafenine ≥98%
1g
$ 80.00

Arctom
Glafenine ≥98%
5g
$ 239.00

Ambeed
2,3-Dihydroxypropyl2-(((7-chloroquinolin-4-yl)amino)benzoate 98+%
5g
$ 189.00

Ambeed
2,3-Dihydroxypropyl2-(((7-chloroquinolin-4-yl)amino)benzoate 98+%
1g
$ 63.00

Ambeed
2,3-Dihydroxypropyl2-(((7-chloroquinolin-4-yl)amino)benzoate 98+%
250mg
$ 23.00

Total 12 raw suppliers

Chemical Property of Glafenine

Chemical Property:

Vapor Pressure:3.92E-16mmHg at 25°C
Melting Point:170℃
Refractive Index:1.6800 (estimate)
Boiling Point:618°Cat760mmHg
PKA:pKa (20°C) 7.2
Flash Point:327.6°C
PSA：91.68000
Density:1.428g/cm³
LogP:3.21480
Storage Temp.:2-8°C(protect from light)
Water Solubility.:38.46g/L(temperature not stated)
XLogP3:3.5
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:372.0876847
Heavy Atom Count:26
Complexity:467

Purity/Quality:

97% ^*data from raw suppliers

Glafenine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Moderately toxic by ingestion. Human systemic effects.
Hazard Codes:Xn
Statements: 22
Safety Statements: 36

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)OCC(CO)O)NC2=C3C=CC(=CC3=NC=C2)Cl
Uses Glafenine is a non-narcotic analgesic agent. Glafenine shows significant antiinflammatory activity. Glafenine is widely used for the treatment of pains of various origins.
Therapeutic Function Analgesic

Technology Process of Glafenine

There total 3 articles about Glafenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 86-98-6,1138471-54-1
4,7-dichloroquinoline

: 71574-35-1
α-Glyceryl Anthranilate

: 3820-67-5
glafenine

Guidance literature:: With hydrogenchloride; In glycerol; at 80 ℃; for 0.666667h;
DOI:10.1055/s-1980-28923

Reference yield:

: 118-48-9
isatoic anhydride

: 3820-67-5
glafenine

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH / 1 h / 80 °C

2: 75 percent / aq. HCl / glycerol / 0.67 h / 80 °C

With hydrogenchloride; sodium hydroxide; In glycerol;
DOI:10.1055/s-1980-28923