(4-Bromo-phenyl)-(3-chloro-1H-indol-7-yl)-methanone

Base Information

Chemical Name:(4-Bromo-phenyl)-(3-chloro-1H-indol-7-yl)-methanone
CAS No.:91714-51-1
Molecular Formula:C15H9BrClNO
Molecular Weight:334.6
Hs Code.:
UNII:ZCT97MC8E4

Synonyms:91714-51-1;(4-Bromophenyl)(3-chloro-1H-indol-7-yl)methanone;(4-Bromo-phenyl)-(3-chloro-1H-indol-7-yl)-methanone;7-(4-BROMOBENZOYL)-3-CHLORO-1H-INDOLE;3-chloro-7-(4-bromobenzoyl)indole;Methanone, (4-bromophenyl)(3-chloro-1H-indol-7-yl)-;ZCT97MC8E4;(4-bromophenyl)-(3-chloro-1H-indol-7-yl)methanone;BCP29808;AKOS000280164;Methanone, (4-broMophenyl)(3-chloro-1H-indol-7-yl)-;3-chloro-7-(4-bromobenzoyl)-indole

Suppliers and Price of (4-Bromo-phenyl)-(3-chloro-1H-indol-7-yl)-methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 26 raw suppliers

Chemical Property of (4-Bromo-phenyl)-(3-chloro-1H-indol-7-yl)-methanone

Chemical Property:

XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:332.95560
Heavy Atom Count:19
Complexity:343

Purity/Quality:: 98%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C(=C1)C(=O)C3=CC=C(C=C3)Br)NC=C2Cl

Technology Process of (4-Bromo-phenyl)-(3-chloro-1H-indol-7-yl)-methanone

There total 4 articles about (4-Bromo-phenyl)-(3-chloro-1H-indol-7-yl)-methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 91714-50-0
7-(4-bromobenzoyl)-1-hydro-indole

: 91714-51-1
(4-Bromo-phenyl)-(3-chloro-1H-indol-7-yl)-methanone

Guidance literature:: With N-chloro-succinimide; In dichloromethane; Ambient temperature;
DOI:10.1021/jm00377a001

Reference yield:

: 496-15-1
1-indoline

: 91714-51-1
(4-Bromo-phenyl)-(3-chloro-1H-indol-7-yl)-methanone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) BCl₃, AlCl₃, 2.) aq. HCl / 1.) toluene, reflux, 20 h, 2.) toluene, reflux, 2.5 h

2: 85 percent / MnO₂ / CH₂Cl₂ / Heating

3: 64 percent / N-chlorosuccinimide / CH₂Cl₂ / Ambient temperature

With hydrogenchloride; manganese(IV) oxide; N-chloro-succinimide; aluminium trichloride; boron trichloride; In dichloromethane;
DOI:10.1021/jm00377a001

Reference yield:

: 623-00-7
4-bromobenzenecarbonitrile

: 91714-51-1
(4-Bromo-phenyl)-(3-chloro-1H-indol-7-yl)-methanone

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) BCl₃, AlCl₃, 2.) aq. HCl / 1.) toluene, reflux, 20 h, 2.) toluene, reflux, 2.5 h

2: 85 percent / MnO₂ / CH₂Cl₂ / Heating

3: 64 percent / N-chlorosuccinimide / CH₂Cl₂ / Ambient temperature

With hydrogenchloride; manganese(IV) oxide; N-chloro-succinimide; aluminium trichloride; boron trichloride; In dichloromethane;
DOI:10.1021/jm00377a001