2(3H)-Oxazolone, 3-butyl-4-(4-fluorophenyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-

Base Information

Chemical Name:2(3H)-Oxazolone, 3-butyl-4-(4-fluorophenyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-
CAS No.:52867-99-9
Molecular Formula:C₂₅H₃₀FN₃O₂
Molecular Weight:423.531
Hs Code.:
DSSTox Substance ID:DTXSID10200897
Wikidata:Q83074074
ChEMBL ID:CHEMBL308056

Synonyms:BRN 1186618;2(3H)-Oxazolone, 3-butyl-4-(4-fluorophenyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-;3-Butyl-4-(4-fluorophenyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-2(3H)-oxazolone;52867-99-9;CHEMBL308056;C25H30FN3O2;DTXSID10200897;LS-100810

Suppliers and Price of 2(3H)-Oxazolone, 3-butyl-4-(4-fluorophenyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 2(3H)-Oxazolone, 3-butyl-4-(4-fluorophenyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-

Chemical Property:

Vapor Pressure:4.49E-12mmHg at 25°C
Boiling Point:548.3°Cat760mmHg
Flash Point:285.4°C
Density:1.17g/cm³
XLogP3:4.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:423.23220537
Heavy Atom Count:31
Complexity:618

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCN1C(=C(OC1=O)CCN2CCN(CC2)C3=CC=CC=C3)C4=CC=C(C=C4)F

Technology Process of 2(3H)-Oxazolone, 3-butyl-4-(4-fluorophenyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)-

There total 5 articles about 2(3H)-Oxazolone, 3-butyl-4-(4-fluorophenyl)-5-(2-(4-phenyl-1-piperazinyl)ethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.3%

: 3-butyl-4-(4-fluorophenyl)-4-hydroxy-5-<2-(4-phenyl-1-piperazinyl)ethyl>-2-oxazolidone

: 52867-99-9
3-butyl-4-(4-fluorophenyl)-5-<2-(4-phenyl-1-piperazinyl)ethyl>-2(3H)-oxazolone

Guidance literature:: With acetic acid; for 1h; Heating;
DOI:10.1021/jm00130a003

Reference yield:

: 51037-47-9
1-(4-fluorophenyl)-2-hydroxy-4-(4-phenyl-1-piperazinyl)-1-butanone

: 52867-99-9
3-butyl-4-(4-fluorophenyl)-5-<2-(4-phenyl-1-piperazinyl)ethyl>-2(3H)-oxazolone

Guidance literature:: Multi-step reaction with 2 steps

1: 2 h / 100 °C

2: 24.3 percent / acetic acid / 1 h / Heating

With acetic acid;
DOI:10.1021/jm00130a003

Reference yield:

: 111-36-4
n-butyl isocyanide

: 52867-99-9
3-butyl-4-(4-fluorophenyl)-5-<2-(4-phenyl-1-piperazinyl)ethyl>-2(3H)-oxazolone

Guidance literature:: Multi-step reaction with 2 steps

1: 2 h / 100 °C

2: 24.3 percent / acetic acid / 1 h / Heating

With acetic acid;
DOI:10.1021/jm00130a003