3-(4-Aminophenyl)piperidine-2,6-dione

Base Information

Chemical Name:3-(4-Aminophenyl)piperidine-2,6-dione
CAS No.:92137-90-1
Molecular Formula:C11H12N2O2
Molecular Weight:204.22500
Hs Code.:
ChEMBL ID:CHEMBL28880
DSSTox Substance ID:DTXSID70546041

Synonyms:3-(4-aminophenyl)piperidine-2,6-dione;92137-90-1;CHEMBL28880;SCHEMBL1553566;DTXSID70546041;BDBM50025053;MFCD24561931;SY311419;3-(4-Amino-phenyl)-piperidine-2,6-dione;CS-0498819;F81321

Suppliers and Price of 3-(4-Aminophenyl)piperidine-2,6-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 3-(4-Aminophenyl)piperidine-2,6-dione

Chemical Property:

Melting Point:139-141 °C(Solv: methanol (67-56-1))
Boiling Point:468.7±45.0 °C(Predicted)
PSA：75.68000
Density:1.261±0.06 g/cm3(Predicted)
LogP:1.64610
XLogP3:0.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:204.089877630
Heavy Atom Count:15
Complexity:270

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)NC(=O)C1C2=CC=C(C=C2)N

Technology Process of 3-(4-Aminophenyl)piperidine-2,6-dione

There total 7 articles about 3-(4-Aminophenyl)piperidine-2,6-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 92137-91-2
3-(4-nitrophenyl)piperidine-2,6-dione

: 92137-90-1
3-(4-Amino-phenyl)-piperidine-2,6-dione

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00158a007

Reference yield:

: 14149-34-9
3-phenyl-2,6-piperidine-dione

: 92137-90-1
3-(4-Amino-phenyl)-piperidine-2,6-dione

Guidance literature:: Multi-step reaction with 2 steps

1: concd H₂SO₄, 63percent aq. HNO₃ / 2 h / -10 - 0 °C

2: H₂ / 10percent Pd/C / ethanol

With sulfuric acid; hydrogen; nitric acid; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00158a007

Reference yield:

: 91137-66-5
2-phenylpentanedinitrile

: 92137-90-1
3-(4-Amino-phenyl)-piperidine-2,6-dione

Guidance literature:: Multi-step reaction with 3 steps

1: 24 percent / concd H₂SO₄, CH₃CO₂H / 6 h

2: concd H₂SO₄, 63percent aq. HNO₃ / 2 h / -10 - 0 °C

3: H₂ / 10percent Pd/C / ethanol

With sulfuric acid; hydrogen; nitric acid; acetic acid; palladium on activated charcoal; In ethanol;
DOI:10.1021/jm00158a007