4'-Chloro-8-((diethylamino)methyl)-7-methoxy-3-methylflavone

Base Information

Chemical Name:4'-Chloro-8-((diethylamino)methyl)-7-methoxy-3-methylflavone
CAS No.:86073-61-2
Molecular Formula:C₂₂H₂₄ClNO₃
Molecular Weight:385.89
Hs Code.:
DSSTox Substance ID:DTXSID10235386
Nikkaji Number:J78.041C
Wikidata:Q83117278

Synonyms:4'-Chloro-8-((diethylamino)methyl)-7-methoxy-3-methylflavone;BRN 5997957;86073-61-2;Flavone, 4'-chloro-8-((diethylamino)methyl)-7-methoxy-3-methyl-;4H-1-Benzopyran-4-one, 2-(4-chlorophenyl)-8-((diethylamino)methyl)-7-methoxy-3-methyl-;4'-Chloro-8-[(diethylamino)methyl]-7-methoxy-3-methylflavone;C22H24ClNO3;C22-H24-Cl-N-O3;DTXSID10235386;LS-68956

Suppliers and Price of 4'-Chloro-8-((diethylamino)methyl)-7-methoxy-3-methylflavone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 4'-Chloro-8-((diethylamino)methyl)-7-methoxy-3-methylflavone

Chemical Property:

Vapor Pressure:1.98E-10mmHg at 25°C
Boiling Point:507.7°Cat760mmHg
Flash Point:260.9°C
Density:1.195g/cm³
XLogP3:5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:385.1444713
Heavy Atom Count:27
Complexity:552

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN(CC)CC1=C(C=CC2=C1OC(=C(C2=O)C)C3=CC=C(C=C3)Cl)OC

Technology Process of 4'-Chloro-8-((diethylamino)methyl)-7-methoxy-3-methylflavone

There total 4 articles about 4'-Chloro-8-((diethylamino)methyl)-7-methoxy-3-methylflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 86073-67-8
3-Methyl-7-methoxy-8-chloromethyl-4'-chloroflavone

: 109-89-7
diethylamine

: 86073-61-2
3-Methyl-7-methoxy-8-diethylaminomethyl-4'-chloroflavone

Guidance literature:: In benzene; for 48h; Ambient temperature;
DOI:10.1002/ardp.19833160507

Reference yield:

: 6270-44-6
2-hydroxy-4-methoxypropiophenone

: 86073-61-2
3-Methyl-7-methoxy-8-diethylaminomethyl-4'-chloroflavone

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / sodium p-chlorobenzoate / 8 h / 180 - 190 °C

2: 80 percent / HCl / acetic acid; aq. HCl / 5 h / 70 - 80 °C

3: 80 percent / benzene / 48 h / Ambient temperature

With hydrogenchloride; sodium p-chlorobenzoate; In hydrogenchloride; acetic acid; benzene;
DOI:10.1002/ardp.19833160507

Reference yield:

: 122-01-0
4-chloro-benzoyl chloride

: 86073-61-2
3-Methyl-7-methoxy-8-diethylaminomethyl-4'-chloroflavone

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / sodium p-chlorobenzoate / 8 h / 180 - 190 °C

2: 80 percent / HCl / acetic acid; aq. HCl / 5 h / 70 - 80 °C

3: 80 percent / benzene / 48 h / Ambient temperature

With hydrogenchloride; sodium p-chlorobenzoate; In hydrogenchloride; acetic acid; benzene;
DOI:10.1002/ardp.19833160507