5-Fluorovaleric acid ethyl ester

Base Information

• Chemical Name: 5-Fluorovaleric acid ethyl ester
• CAS No.: 333-67-5
• Molecular Formula: C7H13FO2
• Molecular Weight: 148.1753
• Hs Code.: 2915900090
• Mol file: 333-67-5.mol

Synonyms:5-fluoro-valeric acid ethyl ester;5-Fluor-valeriansaeure-ethylester;Pentanoic acid,5-fluoro-,ethyl ester;Ethyl 5-fluorovalerate;Valeric acid,5-fluoro-,ethyl ester;5-Fluor-valeriansaeure-aethylester;

Chemical Property of 5-Fluorovaleric acid ethyl ester

Chemical Property:

• Vapor Pressure: 2.8mmHg at 25°C
• Boiling Point: 157.1°Cat760mmHg
• Flash Point: 48.1°C
• PSA: 26.30000
• Density: 0.968g/cm³
• LogP: 1.68930

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Fluorovaleric acid ethyl ester

There total 6 articles about 5-Fluorovaleric acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

δ-chlorovaleronitrile (6280-87-1) → 5-Fluor-valeriansaeure-ethylester (333-67-5)

Guidance literature:

Multi-step reaction with 2 steps

1: diethylene glycol; potassium fluoride / 180 °C

2: hydrogen chloride

With hydrogenchloride; potassium fluoride; diethylene glycol;

DOI:10.1002/hlca.19560390306

Reference yield:

ethanol (64-17-5) + 5-fluoro-valeronitrile (353-13-9) → 5-Fluor-valeriansaeure-ethylester (333-67-5)

Guidance literature:

With hydrogenchloride;

DOI:10.1002/hlca.19560390306

Reference yield:

ethyl 5-bromovalerate (14660-52-7) → 5-Fluor-valeriansaeure-ethylester (333-67-5)

Guidance literature:

With silver fluoride;

upstream raw materials:

ethanol

5-fluoro-valeronitrile

ethyl 5-bromovalerate

ethyl 5-iodopentanoate