(2,5-Dimethoxyphenyl)(4-methoxyphenyl)methanone

Base Information

Chemical Name:(2,5-Dimethoxyphenyl)(4-methoxyphenyl)methanone
CAS No.:80427-23-2
Molecular Formula:C16H16O4
Molecular Weight:272.301
Hs Code.:
NSC Number:86525
DSSTox Substance ID:DTXSID10292939
Wikidata:Q82031453

Synonyms:(2,5-dimethoxyphenyl)(4-methoxyphenyl)methanone;80427-23-2;NSC86525;NCIOpen2_005079;SCHEMBL6375687;DTXSID10292939;SQOVCXYOBMSUHY-UHFFFAOYSA-N;NSC-86525;(2,5-dimethoxyphenyl)(4 methoxyphenyl)methanone;(2,5-Dimethoxy-phenyl)-(4-methoxy-phenyl)-methanone

Suppliers and Price of (2,5-Dimethoxyphenyl)(4-methoxyphenyl)methanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of (2,5-Dimethoxyphenyl)(4-methoxyphenyl)methanone

Chemical Property:

Vapor Pressure:4.43E-08mmHg at 25°C
Boiling Point:444°Cat760mmHg
Flash Point:197.9°C
Density:1.136g/cm³
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:272.10485899
Heavy Atom Count:20
Complexity:310

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(=O)C2=C(C=CC(=C2)OC)OC

Technology Process of (2,5-Dimethoxyphenyl)(4-methoxyphenyl)methanone

There total 3 articles about (2,5-Dimethoxyphenyl)(4-methoxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 100-07-2
4-methoxy-benzoyl chloride

: 150-78-7
1,4-dimethoxybezene

: 80427-23-2
(2,5-dimethoxyphenyl)(4-methoxyphenyl)methanone

Guidance literature:: With tin(IV) chloride; In dichloromethane; at 0 ℃;
DOI:10.1016/0040-4020(96)00815-0

Reference yield: 69.0%

: 146985-16-2
{2,5-(OMe)2-C₆H₃}ZnCl

: 100-07-2
4-methoxy-benzoyl chloride

: 80427-23-2
(2,5-dimethoxyphenyl)(4-methoxyphenyl)methanone

Guidance literature:: With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(II) dichloride; In tetrahydrofuran; diethyl ether; decane; at 60 ℃; for 12h; Inert atmosphere; Schlenk technique;
DOI:10.1055/s-0034-1380697

Reference yield:

: 2100-42-7
2-chloro-1,4-dimethoxybenzene

: 80427-23-2
(2,5-dimethoxyphenyl)(4-methoxyphenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium 4,4′-di-tert-butylbiphenylide / tetrahydrofuran; decane; diethyl ether / 0.08 h / -95 °C / Inert atmosphere; Schlenk technique

1.2: -95 - 20 °C / Inert atmosphere; Schlenk technique

2.1: [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(II) dichloride / tetrahydrofuran; decane; diethyl ether / 12 h / 60 °C / Inert atmosphere; Schlenk technique

With [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene](3-chloropyridyl)palladium(II) dichloride; lithium 4,4′-di-tert-butylbiphenylide; In tetrahydrofuran; diethyl ether; decane;
DOI:10.1055/s-0034-1380697