OCTAETHYLENE GLYCOL MONOMETHYL ETHER

Base Information

• Chemical Name: OCTAETHYLENE GLYCOL MONOMETHYL ETHER
• CAS No.: 25990-96-9
• Molecular Formula: C17H36O9
• Molecular Weight: 384.467
• Hs Code.: 2909499000
• DSSTox Substance ID: DTXSID30335716
• Nikkaji Number: J97.015H
• Mol file: 25990-96-9.mol

Synonyms:2,5,8,11,14,17,20,23-Octaoxapentacosan-25-ol(6CI,8CI,9CI);Methoxyoctaethylene glycol;Octaethylene glycol, monomethylether;

Chemical Property of OCTAETHYLENE GLYCOL MONOMETHYL ETHER

Chemical Property:

• Vapor Pressure: 3.75E-10mmHg at 25°C
• Refractive Index: 1.451
• Boiling Point: 454 °C at 760 mmHg
• PKA: 14.36±0.10(Predicted)
• Flash Point: 228.4 °C
• PSA: 94.07000
• Density: 1.075 g/cm³
• LogP: -0.25870
• Storage Temp.: 2-8°C
• XLogP3: -1.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 23
• Exact Mass: 384.23593272
• Heavy Atom Count: 26
• Complexity: 244

Purity/Quality:

99% ^*data from raw suppliers

2-[2-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCCOCCOCCOCCOCCOCCOCCOCCO
• Description: m-PEG8-alcohol is a PEG linker containing a hydroxyl group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The hydrophilic PEG spacer increases solubility in aqueous media.

Technology Process of OCTAETHYLENE GLYCOL MONOMETHYL ETHER

There total 1 articles about OCTAETHYLENE GLYCOL MONOMETHYL ETHER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Pentaethylene glycol (4792-15-8) + 1-chloro-3,6,9-trioxadecane (52995-76-3) → octaethylene glycol monomethyl ether (25990-96-9)

Guidance literature:

DOI:10.1246/bcsj.51.3111

Reference yield: 98.0%

octaethylene glycol monomethyl ether (25990-96-9) + 4-Vinylbenzyl chloride (1592-20-7,29296-32-0) → 1-(4-vinylphenyl)-2,5,8,11,14,17,20,23,26-nonaoxaheptacosane

Guidance literature:

octaethylene glycol monomethyl ether; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 1.25h; Schlenk technique; Inert atmosphere;

4-Vinylbenzyl chloride; In tetrahydrofuran; for 16h; Schlenk technique; Reflux;

DOI:10.1039/c6gc03528k

Reference yield: 90.0%

octaethylene glycol monomethyl ether (25990-96-9) + p-toluenesulfonyl chloride (98-59-9) → 2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl 4-methylbenzenesulfonate (82217-01-4)

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; water; at 0 - 10 ℃; for 6h;

upstream raw materials:

Pentaethylene glycol

1-chloro-3,6,9-trioxadecane

Downstream raw materials:

methoxypolyethylene glycols-S-triphenylmethyl-L-cysteine dopamine

2--nitrobenzene

2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl 4-methylbenzenesulfonate

1,4-bis(chloromethyl)-2-methoxy-5-(octaethoxymethoxy)benzene