1,2-Dioctanoyl-sn-glycerol

Base Information

Chemical Name:1,2-Dioctanoyl-sn-glycerol
CAS No.:60514-48-9
Molecular Formula:C19H36O5
Molecular Weight:344.4861
Hs Code.:2915900090
DSSTox Substance ID:DTXSID701311778
Nikkaji Number:J429.012G
Wikidata:Q27077094
Metabolomics Workbench ID:71624
ChEMBL ID:CHEMBL55267
Mol file:60514-48-9.mol

Synonyms:1,2-dicapryloylglycerol;1,2-dioctanoyl-rac-glycerol;1,2-dioctanoyl-sn-glycerol;1,2-dioctanoylglycerol;1,2-dioctanoylglycerol, (S)-isomer;diC8;dicaprylglyceride;sn-1,2-dioctanoylglycerol

Suppliers and Price of 1,2-Dioctanoyl-sn-glycerol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
sn-1,2-Dioctanoylglycerol
100mg
$ 425.00

TRC
sn-1,2-Dioctanoylglycerol
25mg
$ 50.00

Sigma-Aldrich
1,2-Dioctanoyl-sn-glycerol Cell-permeable activator of protein kinase C (PKC).
10mg
$ 74.92

Medical Isotopes, Inc.
sn-1,2-Dioctanoylglycerol
100 mg
$ 290.00

Cayman Chemical
1,2-Dioctanoyl-sn-glycerol ≥95%
100mg
$ 136.00

Cayman Chemical
1,2-Dioctanoyl-sn-glycerol ≥95%
50mg
$ 81.00

Cayman Chemical
1,2-Dioctanoyl-sn-glycerol ≥95%
25mg
$ 43.00

American Custom Chemicals Corporation
1,2-DIOCTANOYL-SN-GLYCEROL 95.00%
1G
$ 1593.90

American Custom Chemicals Corporation
1,2-DIOCTANOYL-SN-GLYCEROL 95.00%
100MG
$ 739.20

AK Scientific
1,2-Dioctanoyl-Sn-glycerol
50mg
$ 264.00

Total 17 raw suppliers

Chemical Property of 1,2-Dioctanoyl-sn-glycerol

Chemical Property:

Appearance/Colour:Off-White Solid
Vapor Pressure:3.65E-09mmHg at 25°C
Refractive Index:1.46
Boiling Point:429.1 °C at 760 mmHg
PKA:13.70±0.10(Predicted)
Flash Point:136.8 °C
PSA：72.83000
Density:0.992 g/cm³
LogP:4.15470
Storage Temp.:−20°C
Solubility.:DMSO: soluble
XLogP3:5.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:18
Exact Mass:344.25627424
Heavy Atom Count:24
Complexity:317

Purity/Quality:

99% ^*data from raw suppliers

sn-1,2-Dioctanoylglycerol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 23-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCC
Isomeric SMILES:CCCCCCCC(=O)OC[C@H](CO)OC(=O)CCCCCCC
Uses Cell permeable lipid shown to mimic the effect of tumor-promoting phorbol diesters on mitogenesis and EGF binding and action in intact cells 1,2-Dioctanoyl-sn-glycerol is a cell permeable analog of the PKC-activating second messenger DAG. 1,2-Dioctanoyl-sn-glycerol and 1,2-dioleoyl-sn-glycerol are nearly equipotent in induction of the acrosome reaction in human sperm.[Cayman Chemical] Cell permeable lipid shown to mimic the effect of tumor-promoting phorbol diesters on mitogenesis and EGF binding and action in intact cells.

Technology Process of 1,2-Dioctanoyl-sn-glycerol

There total 5 articles about 1,2-Dioctanoyl-sn-glycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 688021-88-7
1,2-di-O-octanoyl-3-O-benzyl-sn-glycerol

: 60514-48-9
1,2-dioctanoyl-sn-glycerol

Guidance literature:: With hydrogen; acetic acid; palladium on activated charcoal; In ethanol; ethyl acetate; for 18h; under 2068.59 Torr;
DOI:10.1016/j.tet.2006.04.071

Reference yield: 67.0%

: C₂₇H₄₄O₆

: 60514-48-9
1,2-dioctanoyl-sn-glycerol

Guidance literature:: With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; water; at 20 ℃;
DOI:10.1021/jacs.5b05832

Reference yield:

: 111-64-8
n-octanoic acid chloride

: 60514-48-9
1,2-dioctanoyl-sn-glycerol

Guidance literature:: Multi-step reaction with 2 steps

1: 50 percent / pyridine; 4-(dimethylamino)pyridine / 48 h / 55 °C

2: 94 percent / hydrogen; acetic acid / Pd-C / ethanol; ethyl acetate / 18 h / 2068.59 Torr

With pyridine; dmap; hydrogen; acetic acid; palladium on activated charcoal; In ethanol; ethyl acetate;
DOI:10.1016/j.tet.2006.04.071