2-(Diethylamino)-2',4'-acetoxylidide

Base Information

• Chemical Name: 2-(Diethylamino)-2',4'-acetoxylidide
• CAS No.: 17289-53-1
• Molecular Formula: C₁₄H₂₂N₂O
• Molecular Weight: 234.341
• UNII: 1JI90526PD
• DSSTox Substance ID: DTXSID60169420
• Wikidata: Q27252504
• ChEMBL ID: CHEMBL255831
• Mol file: 17289-53-1.mol

Synonyms:2-(Diethylamino)-2',4'-acetoxylidide;2-(diethylamino)-N-(2,4-dimethylphenyl)acetamide;17289-53-1;Acetamide, 2-(diethylamino)-N-(2,4-dimethylphenyl)-;BRN 2648763;2',4'-ACETOXYLIDIDE, 2-(DIETHYLAMINO)-;UNII-1JI90526PD;1JI90526PD;4-12-00-02556 (Beilstein Handbook Reference);CHEMBL255831;SCHEMBL2098794;DTXSID60169420;STL231520;AKOS002844139;LIDOCAINE IMPURITY I [EP IMPURITY];EU-0001446;SR-01000400047;SR-01000400047-1;Q27252504;Z55135893;LIDOCAINE HYDROCHLORIDE IMPURITY I [EP IMPURITY];N-(2,4-dimethylphenyl)-N~2~,N~2~-diethylglycinamide

Chemical Property of 2-(Diethylamino)-2',4'-acetoxylidide

Chemical Property:

• Vapor Pressure: 2.03E-05mmHg at 25°C
• Boiling Point: 361.7°Cat760mmHg
• Flash Point: 172.6°C
• Density: 1.026g/cm³
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 234.173213330
• Heavy Atom Count: 17
• Complexity: 238

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)CC(=O)NC1=C(C=C(C=C1)C)C

Technology Process of 2-(Diethylamino)-2',4'-acetoxylidide

There total 3 articles about 2-(Diethylamino)-2',4'-acetoxylidide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-N-(2,4-dimethylphenyl)acetamide (39106-10-0) + diethylamine (109-89-7) → 2-(diethylamino)-N-(2,4-dimethyl-phenyl)acetamide (17289-53-1)

Guidance literature:

With benzene;

Reference yield:

2,4-Xylidine (95-68-1) → 2-(diethylamino)-N-(2,4-dimethyl-phenyl)acetamide (17289-53-1)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; sodium acetate

2: benzene

With sodium acetate; acetic acid; benzene;

Reference yield:

→ 2-(diethylamino)-N-(2,4-dimethyl-phenyl)acetamide (17289-53-1)

Guidance literature:

Na-Salz v. 2-Dimethylamino-essigsaeure, 1.) Trichloraethylen, Benzoylchlorid, 2.) 2,6-Dimethyl-anilin;

upstream raw materials:

2-chloro-N-(2,4-dimethylphenyl)acetamide

diethylamine

2,4-Xylidine

Refernces