3-Amino-2-(1-phenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one

Base Information

Chemical Name:3-Amino-2-(1-phenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one
CAS No.:92560-78-6
Molecular Formula:C₁₇H₁₃N₅O
Molecular Weight:303.323
Hs Code.:
DSSTox Substance ID:DTXSID30542862
Wikidata:Q82419654

Synonyms:92560-78-6;3-Amino-2-(1-phenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one;3-amino-2-(1-phenyl-1H-pyrazol-4-yl)-3,4-dihydroquinazolin-4-one;DTXSID30542862

Suppliers and Price of 3-Amino-2-(1-phenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Amino-2-(1-phenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one

Chemical Property:

Melting Point:268-270 °C(Solv: N,N-dimethylformamide (68-12-2))
Boiling Point:533.0±42.0 °C(Predicted)
PSA：78.73000
Density:1.39±0.1 g/cm3(Predicted)
LogP:2.54420
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:303.11201006
Heavy Atom Count:23
Complexity:487

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C=C(C=N2)C3=NC4=CC=CC=C4C(=O)N3N

Technology Process of 3-Amino-2-(1-phenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one

There total 3 articles about 3-Amino-2-(1-phenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 92560-77-5
(Z)-3-Dimethylamino-2-(4-oxo-3-{[1-phenyl-meth-(E)-ylidene]-amino}-3,4-dihydro-quinazolin-2-yl)-propenal

: 100-63-0
phenylhydrazine

: 92560-78-6
3-amino-2-(1'-phenylpyrazol-4'-yl)-4-quinazolone

Guidance literature:: In ethanol; 1.) room temp., 2.) warmed, 30 min;

Reference yield:

: 1898-06-2
3-amino-2-methyl-4-oxoquinazoline

: 92560-78-6
3-amino-2-(1'-phenylpyrazol-4'-yl)-4-quinazolone

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / ethanol / 2 h / Heating

2: 61 percent / POCl₃ / 5 h / 55 - 60 °C

3: 68 percent / ethanol / 1.) room temp., 2.) warmed, 30 min

With trichlorophosphate; In ethanol;

Reference yield:

: 56158-74-8
2-methyl-3-(phenylmethylene)-amino-4(3H)quinazolinone

: 92560-78-6
3-amino-2-(1'-phenylpyrazol-4'-yl)-4-quinazolone

Guidance literature:: Multi-step reaction with 2 steps

1: 61 percent / POCl₃ / 5 h / 55 - 60 °C

2: 68 percent / ethanol / 1.) room temp., 2.) warmed, 30 min

With trichlorophosphate; In ethanol;