2-Aminopentan-1-ol

Base Information

• Chemical Name: 2-Aminopentan-1-ol
• CAS No.: 16369-14-5
• Molecular Formula: C₅H₁₃NO
• Molecular Weight: 103.164
• Hs Code.: 29221985
• European Community (EC) Number: 624-183-7
• NSC Number: 66919
• DSSTox Substance ID: DTXSID80936858
• Nikkaji Number: J346.815A
• Mol file: 16369-14-5.mol

Synonyms:2-aminopentan-1-ol;dl-2-Amino-1-pentanol;16369-14-5;DL-Norvalinol;2-Amino-1-pentanol;4146-04-7;D/L-NORVALINOL;1-Pentanol, 2-amino-;2-aminopentanol;MFCD02683228;MFCD02683229;NSC66919;H-Nva-ol;2-amino-pentan-1-ol;2-Amino-1-pentanol #;SCHEMBL352611;DL-2-Amino-1-pentanol, 97%;DTXSID80936858;MFCD00009809;NSC-66919;AKOS009159412;SB44856;SB84058;AS-44290;BP-12648;SY017944;SY038521;CS-0089892;FT-0694471;FT-0694472;EN300-297294

Chemical Property of 2-Aminopentan-1-ol

Chemical Property:

• Vapor Pressure: 0.108mmHg at 25°C
• Melting Point: 32℃
• Refractive Index: n20/D 1.4511(lit.)
• Boiling Point: 195.6°Cat760mmHg
• Flash Point: 95°C
• PSA: 46.25000
• Density: 0.915g/cm³
• LogP: 0.80640
• Storage Temp.: Refrigerator, Under inert atmosphere
• Solubility.: Chloroform (Sparingly), Methanol (Slightly)
• XLogP3: -0.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 103.099714038
• Heavy Atom Count: 7
• Complexity: 39.1

Purity/Quality:

97% ^*data from raw suppliers

DL-2-Amino-1-pentanol ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC(CO)N
• Uses: DL-2-Amino-1-pentanol is a useful intermediate for organic synthesis. It is used in the preparation of amino-substituted pyrimidine derivatives and other aminoethanethiol derivatives with potential antiradiation properties.

Technology Process of 2-Aminopentan-1-ol

There total 22 articles about 2-Aminopentan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

→ DL-2-amino-1-pentanol (4146-04-7,16369-14-5)

Guidance literature:

Reference yield: 86.0%

D-norvaline (2013-12-9,498-18-0) → (2R)-2-aminopentan-1-ol (80696-30-6,16369-14-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; Heating;

DOI:10.1021/jo962090p

Reference yield: 86.0%

→ (2R)-2-aminopentan-1-ol (80696-30-6,16369-14-5)

Guidance literature:

upstream raw materials:

2-nitro-pentan-1-ol

D,L-valine

2-aminopentanoic acid

ethyl 2-aminopentanoate

Downstream raw materials:

4-Propyl-oxazolidon-(2)

Nicotinic acid 2-[(pyridine-3-carbonyl)-amino]-pentyl ester

N-(1-Hydroxymethyl-butyl)-butyramide

(+/-)-2-(acetylamino)pentyl acetate