Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)-

Base Information

Chemical Name:Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)-
CAS No.:927685-43-6
Molecular Formula:C16H14F3NO3
Molecular Weight:325.287
Hs Code.:
UNII:11VWK61J69
NCI Thesaurus Code:C166448
Nikkaji Number:J3.113.482J
Wikidata:Q27251342
Mol file:927685-43-6.mol

Synonyms:2-hydroxy-5-(2-(4-trifluoromethylphenyl)ethylamino)benzoic acid;AAD-2004

Suppliers and Price of Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Hydroxy-5-((4-(trifluoromethyl)phenethyl)amino)benzoicacid 97%
250mg
$ 396.00

Total 10 raw suppliers

Chemical Property of Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)-

Chemical Property:

Melting Point:>300 °C
Boiling Point:496.4±45.0 °C(Predicted)
PKA:2.31±0.10(Predicted)
PSA：69.56000
Density:1.410±0.06 g/cm3(Predicted)
LogP:3.83680
XLogP3:5.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:325.09257779
Heavy Atom Count:23
Complexity:395

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Hydroxy-5-((4-(trifluoromethyl)phenethyl)amino)benzoicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CCNC2=CC(=C(C=C2)O)C(=O)O)C(F)(F)F

Technology Process of Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)-

There total 9 articles about Benzoic acid, 2-hydroxy-5-((2-(4-(trifluoromethyl)phenyl)ethyl)amino)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 1042742-34-6
C₁₉H₁₈F₃NO₄

: 927685-43-6
2-hydroxy-5-[2-(4-(trifluoromethylphenyl)ethylamino)]benzoic acid

Guidance literature:: With hydrogenchloride; acetic acid; for 6h; Heating;
DOI:10.1080/00397910801982001

Reference yield: 84.7%

: 2-hydroxy-5-[2-(4-trifluoromethylphenyl)ethylamino]benzoic acid sulfate

: 927685-43-6
2-hydroxy-5-[2-(4-(trifluoromethylphenyl)ethylamino)]benzoic acid

Guidance literature:: With ammonia; In ethanol; water; pH=3 - 3.5; Industry scale;

Reference yield: 21.0%

: 89-57-6
5-Aminosalicylic Acid

: 130365-87-6
2-[4-(trifluoromethyl)phenyl]ethyl bromide

: 927685-43-6
2-hydroxy-5-[2-(4-(trifluoromethylphenyl)ethylamino)]benzoic acid

Guidance literature:: 5-Aminosalicylic Acid; With triethylamine; tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h; Inert atmosphere;

2-[4-(trifluoromethyl)phenyl]ethyl bromide; In N,N-dimethyl-formamide; at 20 ℃; for 3h;