benzyl 1,8-diazaspiro[4.5]decane-8-carboxylate hydrochloride

Base Information

• Chemical Name: benzyl 1,8-diazaspiro[4.5]decane-8-carboxylate hydrochloride
• CAS No.: 928034-35-9
• Molecular Formula: C₁₆H₂₂N₂O₂*ClH
• Molecular Weight: 310.824

Synonyms:1,8-Diazaspiro[4.5]decane-8-carboxylic acid, phenylMethyl ester, (Hydrochloride) (1:1)

Chemical Property of benzyl 1,8-diazaspiro[4.5]decane-8-carboxylate hydrochloride

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzyl 1,8-diazaspiro[4.5]decane-8-carboxylate hydrochloride

There total 1 articles about benzyl 1,8-diazaspiro[4.5]decane-8-carboxylate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

8-benzyl 1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate (928034-34-8) → 8-[(benzyloxy)carbonyl]-8-aza-1-azoniaspiro[4.5]decane chloride (928034-35-9)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; at 0 - 20 ℃; for 24h;

Reference yield:

8-[(benzyloxy)carbonyl]-8-aza-1-azoniaspiro[4.5]decane chloride (928034-35-9) + benzenesulfonyl chloride (98-09-9) → benzyl 1-(phenylsulfonyl)-1,8-diazaspiro[4.5]decane-8-carboxylate (928034-36-0)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 72h;

upstream raw materials:

8-benzyl 1-tert-butyl 1,8-diazaspiro[4.5]decane-1,8-dicarboxylate

Downstream raw materials:

benzyl 1-(phenylsulfonyl)-1,8-diazaspiro[4.5]decane-8-carboxylate

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