7-Hydroxy-2-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one

Base Information

Chemical Name:7-Hydroxy-2-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one
CAS No.:551-15-5
Molecular Formula:C21H22O9
Molecular Weight:418.4
Hs Code.:29389090
Wikidata:Q104977346
Mol file:551-15-5.mol

Synonyms:7-hydroxy-2-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one;Oprea1_694225;SCHEMBL13931703;SCHEMBL24209243;HMS3345A09;FT-0686655

Suppliers and Price of 7-Hydroxy-2-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Liquiritin
20mg
$ 320.00

Usbiological
Liquiritin
10mg
$ 403.00

Usbiological
Liquiritin
25mg
$ 535.00

TRC
Liquiritin
250mg
$ 675.00

Sigma-Aldrich
Liquiritin ≥98% (HPLC)
10mg
$ 160.00

Sigma-Aldrich
Liquiritin ≥98% (HPLC)
50mg
$ 591.00

Medical Isotopes, Inc.
Liquiritin
25 mg
$ 675.00

JR MediChem
Liquiritin?(NewProduct) 98%
1g
$ 880.00

JR MediChem
Liquiritin?(NewProduct) 98%
5g
$ 3980.00

JR MediChem
Liquiritin?(NewProduct) 98%
500mg
$ 518.00

Total 101 raw suppliers

Chemical Property of 7-Hydroxy-2-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one

Chemical Property:

Vapor Pressure:2.01E-23mmHg at 25°C
Melting Point:208 °C(Solv: ethanol (64-17-5))
Refractive Index:1.67
Boiling Point:746.8 °C at 760 mmHg
PKA:7.70±0.40(Predicted)
Flash Point:265.9 °C
PSA：145.91000
Density:1.529 g/cm³
LogP:0.27740
Storage Temp.:2-8°C
Solubility.:DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
XLogP3:0.4
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:4
Exact Mass:418.12638228
Heavy Atom Count:30
Complexity:593

Purity/Quality:

95%-98% ^*data from raw suppliers

Liquiritin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC2=C(C1=O)C=CC(=C2)O)C3=CC=C(C=C3)OC4C(C(C(C(O4)CO)O)O)O
Uses Liquiritin is a major constituent of Glycyrrhiza Radix that has a neuroprotective effect against glutamate toxicity in DPC12 cells and may have potential for the treatment of neurodegenerative diseases.

Technology Process of 7-Hydroxy-2-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one

There total 2 articles about 7-Hydroxy-2-[4-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-2,3-dihydrochromen-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₉H₁₀FNO

: 485404-58-8
[2-(2-fluoro-phenyl)-ethyl]-methyl-amine

Guidance literature:: With borane-THF; In tetrahydrofuran; for 2h; Heating;
DOI:10.1016/j.bmc.2008.06.009

Reference yield:

: liquiritin apioside

: 551-15-5
liquiritin(sh)

Guidance literature:: With ion exchange resin (Dowex 50W x 8); In methanol; for 6h; Product distribution; Ambient temperature;
DOI:10.1016/S0031-9422(00)83548-7