Ethanone, 2-amino-1-[4-(phenylmethoxy)phenyl]-

Base Information

Chemical Name:Ethanone, 2-amino-1-[4-(phenylmethoxy)phenyl]-
CAS No.:92850-54-9
Molecular Formula:C15H15NO2
Molecular Weight:241.29
Hs Code.:
DSSTox Substance ID:DTXSID60561884
Nikkaji Number:J2.941.060G
Wikidata:Q82445803

Synonyms:92850-54-9;Ethanone, 2-amino-1-[4-(phenylmethoxy)phenyl]-;2-amino-1-(4-phenylmethoxyphenyl)ethanone;SCHEMBL2013554;DTXSID60561884;YHJKYNMAHQSKPP-UHFFFAOYSA-N;2-amino-1-(4-benzyloxyphenyl)ethanone;2-Amino-1-(4-(benzyloxy)phenyl)ethanone;2-Amino-1-[4-(benzyloxy)phenyl]ethan-1-one

Suppliers and Price of Ethanone, 2-amino-1-[4-(phenylmethoxy)phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Ethanone, 2-amino-1-[4-(phenylmethoxy)phenyl]-

Chemical Property:

PSA：52.32000
LogP:3.10730
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:241.110278721
Heavy Atom Count:18
Complexity:253

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=CC=C(C=C2)C(=O)CN

Technology Process of Ethanone, 2-amino-1-[4-(phenylmethoxy)phenyl]-

There total 6 articles about Ethanone, 2-amino-1-[4-(phenylmethoxy)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 100-97-0
hexamethylenetetramine

: 63365-56-0
1-(4-(benzyloxy)phenyl)-2-chloroethanone

: 92850-54-9
2-amino-1-(4-benzyloxy-phenyl)-ethanone

Guidance literature:: With hydrogenchloride; In ethanol; chloroform;

Reference yield:

: 15028-44-1
DL-phenylalanine methyl ester

: 99-93-4
4-Hydroxyacetophenone

: 92850-54-9
2-amino-1-(4-benzyloxy-phenyl)-ethanone

Guidance literature:: DL-phenylalanine methyl ester; With potassium carbonate; In methanol; at 20 ℃;

4-Hydroxyacetophenone; In methanol; for 1h;
DOI:10.1021/acs.joc.5b01770

Reference yield:

: N-[2-(4-hydroxyphenyl)-2-oxoethyl]phenylalanine hydrochloride methyl ester

: 92850-54-9
2-amino-1-(4-benzyloxy-phenyl)-ethanone

Guidance literature:: Multi-step reaction with 2 steps

1.1: aq. phosphate buffer / pH 5.6 / Irradiation

2.1: potassium carbonate / methanol / 20 °C

2.2: 1 h

With potassium carbonate; In methanol; aq. phosphate buffer; 2.2: |Favorskii Rearrangement;
DOI:10.1021/acs.joc.5b01770