Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-, acetate

Base Information

Chemical Name:Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-, acetate
CAS No.:16562-72-4
Molecular Formula:C16H19 N O5
Molecular Weight:305.3258
Hs Code.:2934999090
Nikkaji Number:J41.786F
Wikidata:Q76387044
Mol file:16562-72-4.mol

Synonyms:16562-72-4;Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-, acetate;LG 50,159;[2-methoxy-4-[(E)-3-morpholin-4-yl-3-oxoprop-1-enyl]phenyl] acetate;4-[3-(4-Acetoxy-3-methoxyphenyl)-1-oxo-2-propenyl]morpholine;NLDFRYFDOLAMCA-GQCTYLIASA-N;LG-50159;LS-93054;Morpholine, 4-[3-[4-(acetyloxy)-3-methoxyphenyl]-1-oxo-2-propenyl]-

Suppliers and Price of Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-, acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-, acetate

Chemical Property:

Vapor Pressure:9.89E-10mmHg at 25°C
Boiling Point:489.5°Cat760mmHg
PKA:-1.07±0.20(Predicted)
Flash Point:249.9°C
PSA：65.07000
Density:1.219g/cm³
LogP:1.43040
XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:305.12632271
Heavy Atom Count:22
Complexity:417

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1=C(C=C(C=C1)C=CC(=O)N2CCOCC2)OC
Isomeric SMILES:CC(=O)OC1=C(C=C(C=C1)/C=C/C(=O)N2CCOCC2)OC

Technology Process of Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-, acetate

There total 5 articles about Morpholine, 4-(4-hydroxy-3-methoxycinnamoyl)-, acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 34749-55-8,147677-05-2,2596-47-6
3-(4-acetoxy-3-methoxyphenyl)prop-2-enoic acid

: 16562-72-4
4-[3-(4-acetoxy-3-methoxy-phenyl)-acryloyl]-morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 0 °C

2: triethylamine / dichloromethane / 2 h / 0 °C

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1002/ardp.201500317

Reference yield:

: 121-33-5,8014-42-4
vanillin

: 16562-72-4
4-[3-(4-acetoxy-3-methoxy-phenyl)-acryloyl]-morpholine

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine; aniline / toluene / 4 h / Reflux

2: dmap / 0 - 10 °C

3: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 0 °C

4: triethylamine / dichloromethane / 2 h / 0 °C

With pyridine; dmap; oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; aniline; In dichloromethane; toluene;
DOI:10.1002/ardp.201500317

Reference yield:

: 1135-24-6,537-98-4
3-(4-hydroxy-3-methoxyphenyl)acrylic acid

: 16562-72-4
4-[3-(4-acetoxy-3-methoxy-phenyl)-acryloyl]-morpholine

Guidance literature:: Multi-step reaction with 3 steps

1: dmap / 0 - 10 °C

2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 0 °C

3: triethylamine / dichloromethane / 2 h / 0 °C

With dmap; oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;
DOI:10.1002/ardp.201500317