3-Benzhydryl-8-methyl-3,8-diazabicyclo[3.2.1]octane

Base Information

Chemical Name:3-Benzhydryl-8-methyl-3,8-diazabicyclo[3.2.1]octane
CAS No.:63978-04-1
Molecular Formula:C20H24 N2
Molecular Weight:292.418
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10981452
Nikkaji Number:J68.436H
Mol file:63978-04-1.mol

Synonyms:63978-04-1;BRN 0546036;3-benzhydryl-8-methyl-3,8-diazabicyclo[3.2.1]octane;3-(diphenylmethyl)-8-methyl-3,8-diazabicyclo[3.2.1]octane;8-Methyl-3-(diphenylmethyl)-3,8-diazabicyclo(3.2.1)octane;3,8-Diazabicyclo(3.2.1)octane, 3-(diphenylmethyl)-8-methyl-;3,8-Diazabicyclo(3.2.1)octane, 8-methyl-3-(diphenylmethyl)-;DTXSID10981452

Suppliers and Price of 3-Benzhydryl-8-methyl-3,8-diazabicyclo[3.2.1]octane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Benzhydryl-8-methyl-3,8-diazabicyclo[3.2.1]octane

Chemical Property:

Vapor Pressure:1.95E-06mmHg at 25°C
Boiling Point:394.7°Cat760mmHg
Flash Point:174.9°C
PSA：6.48000
Density:1.094g/cm³
LogP:3.43020
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:292.193948774
Heavy Atom Count:22
Complexity:325

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C2CCC1CN(C2)C(C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 3-Benzhydryl-8-methyl-3,8-diazabicyclo[3.2.1]octane

There total 6 articles about 3-Benzhydryl-8-methyl-3,8-diazabicyclo[3.2.1]octane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 51102-42-2
8-methyl-3,8-diazabicyclo[3,2,1]octane

: 90-99-3
diphenylchloromethane

: 63978-04-1
3-benzhydryl-8-methyl-3,8-diaza-bicyclo[3.2.1]octane

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 60 - 65 ℃; for 7h;
DOI:10.1016/j.tetlet.2006.11.141

Reference yield:

: methyl (E)-1-methyl-5-(nitromethylene)pyrrolidine-2-carboxylate

: 63978-04-1
3-benzhydryl-8-methyl-3,8-diaza-bicyclo[3.2.1]octane

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / HCO₂NH₄ / Pd-C / methanol / Heating

2: 77 percent / LAH / tetrahydrofuran / 6 h / Heating

3: 49 percent / K₂CO₃ / dimethylformamide / 7 h / 60 - 65 °C

With lithium aluminium tetrahydride; ammonium formate; potassium carbonate; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2006.11.141

Reference yield:

: methyl 1-methyl-5-thioxopyrrolidine-2-carboxylate

: 63978-04-1
3-benzhydryl-8-methyl-3,8-diaza-bicyclo[3.2.1]octane

Guidance literature:: Multi-step reaction with 5 steps

1: 95 percent / benzene / 12 h / 20 °C

2: 65 percent / Et₃N / dimethylformamide / 24 h / 20 °C

3: 79 percent / HCO₂NH₄ / Pd-C / methanol / Heating

4: 77 percent / LAH / tetrahydrofuran / 6 h / Heating

5: 49 percent / K₂CO₃ / dimethylformamide / 7 h / 60 - 65 °C

With lithium aluminium tetrahydride; ammonium formate; potassium carbonate; triethylamine; palladium on activated charcoal; In tetrahydrofuran; methanol; N,N-dimethyl-formamide; benzene;
DOI:10.1016/j.tetlet.2006.11.141