2,4-Dimethylglutaric acid diethyl ester

Base Information

• Chemical Name: 2,4-Dimethylglutaric acid diethyl ester
• CAS No.: 21239-22-5
• Molecular Formula: C11H20O4
• Molecular Weight: 216.277
• Hs Code.: 2917190090
• Mol file: 21239-22-5.mol

Synonyms:Diethyl 2,4-dimethylglutarate;Pentanedioic acid, 2,4-dimethyl-, diethyl ester;2,4-Pentandicarbonsaeurediethylester;2,4-Dimethylglutarsaeurediethylester;

Chemical Property of 2,4-Dimethylglutaric acid diethyl ester

Chemical Property:

• Vapor Pressure: 0.0639mmHg at 25°C
• Boiling Point: 231°Cat760mmHg
• Flash Point: 103.1°C
• PSA: 52.60000
• Density: 0.992g/cm³
• LogP: 1.77490

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,4-Dimethylglutaric acid diethyl ester

There total 2 articles about 2,4-Dimethylglutaric acid diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanol (64-17-5) + 2,4-dimethylglutaric acid (2121-67-7) → racem.-2,4-dimethyl-glutaric acid diethyl ester; 2,4-dimethyl-glutaric acid diethyl ester (21239-22-5,34022-15-6,34022-16-7)

Guidance literature:

With sulfuric acid;

Reference yield:

→ Diethyl 2,4-dimethylglutarate (21239-22-5)

Guidance literature:

entspr. Diester (19), Dabco (2);

DOI:10.1021/jo00864a006

Reference yield:

Diethyl 2,4-dimethylglutarate (21239-22-5) → 2-hydroxy-3,5-dimethyl-2-cyclopenten-1-one (21834-98-0)

Guidance literature:

Multi-step reaction with 3 steps

1: Na / toluene

2: aq. HCl / tetrahydrofuran

3: Cu(OAc)2 / aq. acetic acid

With hydrogenchloride; copper diacetate; sodium; In tetrahydrofuran; acetic acid; toluene;

upstream raw materials:

ethanol

2,4-dimethylglutaric acid

Downstream raw materials:

2-hydroxy-3,5-dimethyl-2-cyclopenten-1-one