Benzenecarboximidic acid, N-[2-[2-(methoxymethyl)-1-pyrrolidinyl]-2-oxoethyl]-, (1,1-dimethylethyl)dimethylsilyl ester, (S)-

Base Information

• Chemical Name: Benzenecarboximidic acid, N-[2-[2-(methoxymethyl)-1-pyrrolidinyl]-2-oxoethyl]-, (1,1-dimethylethyl)dimethylsilyl ester, (S)-
• CAS No.: 93273-96-2
• Molecular Formula: C21H34N2O3Si
• Molecular Weight: 390.598
• Mol file: 93273-96-2.mol

Synonyms:

Chemical Property of Benzenecarboximidic acid, N-[2-[2-(methoxymethyl)-1-pyrrolidinyl]-2-oxoethyl]-, (1,1-dimethylethyl)dimethylsilyl ester, (S)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenecarboximidic acid, N-[2-[2-(methoxymethyl)-1-pyrrolidinyl]-2-oxoethyl]-, (1,1-dimethylethyl)dimethylsilyl ester, (S)-

There total 3 articles about Benzenecarboximidic acid, N-[2-[2-(methoxymethyl)-1-pyrrolidinyl]-2-oxoethyl]-, (1,1-dimethylethyl)dimethylsilyl ester, (S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S)-2-(methoxymethyl)-1-pyrrolidine (63126-47-6) → C21H34N2O3Si (93273-96-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,1'-carbonyldiimidazole

2: 1.) LDA / 1.) THF, hexane, -78 deg C, 1.5 h; 2.) THF, hexane, -5 deg C, 0.5 h

With 1,1'-carbonyldiimidazole; lithium diisopropyl amide;

Reference yield:

Hippuric Acid (495-69-2,140480-84-8,21251-67-2,91787-63-2,66407-11-2) → C21H34N2O3Si (93273-96-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,1'-carbonyldiimidazole

2: 1.) LDA / 1.) THF, hexane, -78 deg C, 1.5 h; 2.) THF, hexane, -5 deg C, 0.5 h

With 1,1'-carbonyldiimidazole; lithium diisopropyl amide;

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) + N-benzoyl-glycine (S)-prolinol methyl ether amide (93273-92-8) → C21H34N2O3Si (93273-96-2)

Guidance literature:

With lithium diisopropyl amide; Yield given. Multistep reaction; 1.) THF, hexane, -78 deg C, 1.5 h; 2.) THF, hexane, -5 deg C, 0.5 h;

upstream raw materials:

tert-butyldimethylsilyl chloride

N-benzoyl-glycine (S)-prolinol methyl ether amide

Hippuric Acid

(2S)-2-(methoxymethyl)-1-pyrrolidine