Technology Process of 3-Pyridinecarboxylic acid, 5-(3-aminophenyl)-, methyl ester
There total 5 articles about 3-Pyridinecarboxylic acid, 5-(3-aminophenyl)-, methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium on activated charcoal;
In
methanol; acetic acid methyl ester;
for 8h;
under 2585.7 Torr;
DOI:10.1021/jo00200a045
- Guidance literature:
-
Multi-step reaction with 5 steps
1: SOCl2 / neat (no solvent) / 24 h / Heating
2: bromine / 1 h / 150 °C
3: CH2Cl2 / 1. ice bath 2. 30 min reflux
4: 40 percent / Copper bronze / Pd(OAc)2, tri-o-tolylphosphine, NEt3 / dimethylformamide / 8 h / 180 °C
5: 96 percent / hydrogen / 5percent Pd on Carbon / methanol; methyl acetate / 8 h / 2585.7 Torr
With
thionyl chloride; hydrogen; bromine; copper;
palladium diacetate; palladium on activated charcoal; triethylamine; tris-(o-tolyl)phosphine;
In
methanol; dichloromethane; acetic acid methyl ester; N,N-dimethyl-formamide;
DOI:10.1021/jo00200a045
- Guidance literature:
-
Multi-step reaction with 3 steps
1: CH2Cl2 / 1. ice bath 2. 30 min reflux
2: 40 percent / Copper bronze / Pd(OAc)2, tri-o-tolylphosphine, NEt3 / dimethylformamide / 8 h / 180 °C
3: 96 percent / hydrogen / 5percent Pd on Carbon / methanol; methyl acetate / 8 h / 2585.7 Torr
With
hydrogen; copper;
palladium diacetate; palladium on activated charcoal; triethylamine; tris-(o-tolyl)phosphine;
In
methanol; dichloromethane; acetic acid methyl ester; N,N-dimethyl-formamide;
DOI:10.1021/jo00200a045
