4-Amino-3-chlorobenzaldehyde

Base Information

• Chemical Name: 4-Amino-3-chlorobenzaldehyde
• CAS No.: 93359-88-7
• Molecular Formula: C7H6ClNO
• Molecular Weight: 155.584
• European Community (EC) Number: 854-297-4
• DSSTox Substance ID: DTXSID60535520
• Nikkaji Number: J532.740G
• Wikidata: Q82409846
• Mol file: 93359-88-7.mol

Synonyms:4-amino-3-chlorobenzaldehyde;93359-88-7;3-chloro-4-aminobenzaldehyde;4-amino-3-chloroben-zaldehyde;SCHEMBL3935932;DTXSID60535520;FNTUAAGLCQIYTB-UHFFFAOYSA-N;AKOS013464341;CS-0223593;EN300-115933;Z1198314265

Chemical Property of 4-Amino-3-chlorobenzaldehyde

Chemical Property:

• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 155.0137915
• Heavy Atom Count: 10
• Complexity: 129

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1C=O)Cl)N

Technology Process of 4-Amino-3-chlorobenzaldehyde

There total 1 articles about 4-Amino-3-chlorobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-chloro-4-methyl-benzenamine (615-65-6) → 4-amino-3-chlorobenzaldehyde (93359-88-7)

Guidance literature:

With hydrogenchloride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In water; at 20 ℃; for 2h; regiospecific reaction;

DOI:10.1016/j.cclet.2011.03.016

Reference yield: 55.7%

5-(3-chloro-4-isopropoxyphenyl)isoxazole-3-carboxylic acid (1105635-32-2) + 4-amino-3-chlorobenzaldehyde (93359-88-7) → N-(2-chloro-4-formylphenyl)-5-(3-chloro-4-isopropoxyphenyl)-isoxazole-3-carboxamide (1105634-61-4)

Guidance literature:

With pyridine; trichlorophosphate; at -15 ℃; for 1h;

Reference yield:

6-hydroxybenzofuran-3-one (6272-26-0) + 4-amino-3-chlorobenzaldehyde (93359-88-7) → 2-[(3-chloro-4-aminophenyl)methylene]-6-hydroxy-3(2H)-benzofuranone

Guidance literature:

With hydrogenchloride; In methanol;

upstream raw materials:

2-chloro-4-methyl-benzenamine

Downstream raw materials:

N-(2-chloro-4-formylphenyl)-5-(3-chloro-4-isopropoxyphenyl)-isoxazole-3-carboxamide