10h-Phenothiazin-10-yl(phenyl)methanone

Base Information

• Chemical Name: 10h-Phenothiazin-10-yl(phenyl)methanone
• CAS No.: 38076-73-2
• Molecular Formula: C19H13NOS
• Molecular Weight: 303.384
• European Community (EC) Number: 660-533-5
• NSC Number: 95774
• UNII: 9HA99HYS3S
• DSSTox Substance ID: DTXSID00294306
• Nikkaji Number: J390.549G
• Wikidata: Q82033539
• ChEMBL ID: CHEMBL239400
• Mol file: 38076-73-2.mol

Synonyms:10h-phenothiazin-10-yl(phenyl)methanone;10-benzoylphenothiazine;phenothiazin-10-yl(phenyl)methanone;38076-73-2;n-benzoylphenothiazine;9HA99HYS3S;Phenothiazine, 10-benzoyl-;NSC-95774;10H-Phenothiazine, 10-benzoyl-;UNII-9HA99HYS3S;10H-Phenothiazin-10-ylphenylmethanone;Methanone, 10H-phenothiazin-10-ylphenyl-;CHEMBL239400;10-BENZOYL-10H-PHENOTHIAZINE;NSC95774;(10H-phenothiazin-10-yl)(phenyl)methanone;Oprea1_507390;Oprea1_637573;SCHEMBL343497;DTXSID00294306;BDBM50219217;STL371969;AKOS000279791;PD177878

Chemical Property of 10h-Phenothiazin-10-yl(phenyl)methanone

Chemical Property:

• Vapor Pressure: 5.55E-09mmHg at 25°C
• Boiling Point: 469.4°Cat760mmHg
• Flash Point: 237.7°C
• Density: 1.298g/cm³
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 303.07178521
• Heavy Atom Count: 22
• Complexity: 384

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)N2C3=CC=CC=C3SC4=CC=CC=C42

Technology Process of 10h-Phenothiazin-10-yl(phenyl)methanone

There total 4 articles about 10h-Phenothiazin-10-yl(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

10H-phenothiazine (92-84-2) + benzoyl chloride (98-88-4) → (10H-phenothiazin-10-yl)(phenyl)methanone (38076-73-2)

Guidance literature:

In toluene; Reflux;

DOI:10.1021/jm200436t

Reference yield: 84.0%

10-benzoyl-10H-phenothiazine-5-oxide (62409-50-1) → (10H-phenothiazin-10-yl)(phenyl)methanone (38076-73-2)

Guidance literature:

With titanium(IV) iodide; In acetonitrile; at 0 ℃; for 0.166667h;

Reference yield:

2-ethanesulfonylmethyl-5-bromo-thiophene (98546-66-8) + benzoyl chloride (98-88-4) → (10H-phenothiazin-10-yl)(phenyl)methanone (38076-73-2)

Guidance literature:

With ligroine; at 100 ℃; im Rohr;

upstream raw materials:

2-ethanesulfonylmethyl-5-bromo-thiophene

benzoyl chloride

10H-phenothiazine

10-benzoyl-10H-phenothiazine-5-oxide

Downstream raw materials:

10-benzoyl-10H-5λ⁴-phenothiazin-5-ylideneamine

10-benzoyl-5-oxo-5,10-dihydro-5λ⁶-phenothiazin-5-ylideneamine

10-benzoyl-10H-phenothiazine-5-oxide

(5,5-dioxido-10H-phenothiazin-10-yl)(phenyl)methanone