Technology Process of N-Methyl-3-piperidyl benzilate
There total 7 articles about N-Methyl-3-piperidyl benzilate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
piperidin-3-yl 2-hydroxy-2,2-diphenylacetate;
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 0.25h;
Inert atmosphere;
methyl iodide;
In
N,N-dimethyl-formamide;
at 0 - 25 ℃;
for 3h;
- Guidance literature:
-
With
n-heptane; sodium methylate;
unter Abdestillieren des Methanols;
DOI:10.1021/ja01613a068
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium / benzene / 2.5 h / Reflux
1.2: Reflux
2.1: palladium 10% on activated carbon; hydrogen / methanol; ethyl acetate / 3 h / 20 °C
3.1: potassium carbonate / N,N-dimethyl-formamide / 0.25 h / 0 °C / Inert atmosphere
3.2: 3 h / 0 - 25 °C
With
palladium 10% on activated carbon; hydrogen; sodium; potassium carbonate;
In
methanol; ethyl acetate; N,N-dimethyl-formamide; benzene;
