52182-15-7

Basic information

• Product Name: ETHYL BENZILATE
• Synonyms: BENZILIC ACID ETHYL ESTER;ETHYL BENZILATE;ETHYL DIPHENYLGLYCOLATE;DIPHENYLGLYCOLIC ACID ETHYL ESTER;Ethyl benzillate;BENZILIC ACID ETHYL ESTER 97%;Ethyl benzilate, 97+%;Diphenylhydroxyacetic acid ethyl ester
• CAS NO: 52182-15-7
• Molecular Formula: C₁₆H₁₆O₃
• Molecular Weight: 256.3
• EINECS: 257-713-7
• Product Categories: Aromatic Esters
• Mol File: 52182-15-7.mol
• Article Data: 11

Chemical Properties

• Melting Point: 29°C
• Boiling Point: 192-194°C 12mm
• Flash Point: 192-194°C/12mm
• Appearance: /
• Density: 1,562 g/cm3
• Vapor Pressure: 4.55E-05mmHg at 25°C
• Refractive Index: 1.5600
• BRN: 991958
• CAS DataBase Reference: ETHYL BENZILATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL BENZILATE(52182-15-7)
• EPA Substance Registry System: ETHYL BENZILATE(52182-15-7)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 52182-15-7(Hazardous Substances Data)

Usage

General Description

Ethyl Benzilate, also known as benzilic acid ethyl ester, is an organic compound with the formula C15H14O3. It belongs to the class of compounds called benzyl esters and is utilized in various industries for its aromatic characteristics. Ethyl Benzilate is primarily used as a fragrance in cosmetics and personal care products, as well as a flavoring agent in food and beverages. Its scent is reminiscent of flowers, fruity notes, and spices, and it is used as an intermediate product in chemical synthesis. While it is generally stable under normal conditions, it may cause irritation upon contact with skin or eyes and can decompose to potentially hazardous fumes if exposed to high heat. Handling methods and disposal considerations for Ethyl Benzilate should follow standard safety protocols for potentially harmful chemicals.

InChI:InChI=1/C16H16O3/c1-2-19-15(17)16(18,13-9-5-3-6-10-13)14-11-7-4-8-12-14/h3-12,18H,2H2,1H3

Upstream product

• 4755-77-5 Ethyl oxalyl chloride 
• 114570-16-0 (2,3-Dimethyl-benzo[g]indol-1-yl)-oxo-acetic acid ethyl ester 
• 64-17-5 ethanol 
• 76-93-7 Benzilic acid 
• 2902-98-9 2-chloro-2,2-diphenylacetyl chloride 
• 611-73-4 Benzoylformic acid 
• 134-81-6 benzil 
• 119-61-9 benzophenone 
• 105-36-2 ethyl bromoacetate 
• 25726-04-9 phenylglyoxylyl chloride 
• 1603-79-8 phenylglyoxylic acid ethyl ester 
• 143-66-8 sodium tetraphenyl borate 
• 98-80-6 phenylboronic acid 
• 934-56-5 trimethyl(phenyl)stannane 

Downstream Products

• 3608-67-1 N-methyl-4-piperidyl benzilate 
• 4546-39-8 benzilic acid-(2-piperidino-ethyl ester) 
• 2819-40-1 3,5,5-triphenyl-oxazolidine-2,4-dione 
• 1164-41-6 N-(2-diethylamino-ethyl)-benzilamide 
• 4406-92-2 O-Acetyl-benzilsaeure-aethylester 
• 5841-23-6 3-methyl-5,5-diphenyl-oxazolidine-2,4-dione 
• 5554-37-0 benzilanilide 
• 4171-11-3 5,5-Diphenyl-1,3-oxazolidin-2,4-dion 
• 302-40-9 benactyzine 
• 116009-94-0 benzilic acid-(6exo,7exo-dimethoxy-tropane-3exo-yl ester) 
• 116179-15-8 benzilic acid-(6exo,7exo-dimethoxy-tropane-3endo-yl ester) 
• 77308-09-9 5,5-diphenyl-3-propyl-oxazolidine-2,4-dione 
• 7472-45-9 2,2-Diphenyl-2-hydroxy-N-methylacetamide 
• 76-93-7 Benzilic acid 

Relevant articles and documents

NOVEL COMPOUNDS AS ANTI-TUBERCULAR AGENTS

The present invention relates to novel compounds of formula (1): The present invention also discloses compounds of formula (1) along with other pharmaceutical acceptable excipients and use of the compounds as anti-tubercular agents.

One-pot synthesis of cyclophane-type macrocycles using manganese(iii)- mediated oxidative radical cyclization

Cyclophane-type macrocyclic compounds from 21 to 56 members having two fused dihydrofuran rings were synthesized by the manganese(iii)-mediated oxidation of terminal dienes with bis(3-oxobutanoate)s containing aromatics. The reaction detail, characterization and reaction pathways are described. The Royal Society of Chemistry 2011.

Anionic four-electron donor-based palladacycles as catalysts for addition reactions of arylboronic acids with α,β-unsaturated ketones, aldehydes, and α-ketoesters

(Chemical Equation Presented) Anionic four-electron donor-based palladacycle-catalyzed 1,4-additions of arylboronic acids with α,β-unsaturated ketones and 1,2-additions of arylboronic acids with aldehydes and α-ketoesters are described. Our study demonstrated that palladacycles were highly efficient, practical catalysts for these addition reactions. The work described here not only opened a new paradigm for the application of palladacycles, but may also pave the road for other metalacycles as practically useful catalysts for such addition reactions including asymmetric ones.