VEDACLIDINE

Base Information

Chemical Name:VEDACLIDINE
CAS No.:141593-42-2
Molecular Formula:C₁₃H₂₁N₃S₂
Molecular Weight:283.462
Hs Code.:
Mol file:141593-42-2.mol

Synonyms:1,2,5-Thiadiazole,1-azabicyclo[2.2.2]octane deriv.; LY 297802

Suppliers and Price of VEDACLIDINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
VEDACLIDINE 95.00%
5MG
$ 501.41

Total 1 raw suppliers

Chemical Property of VEDACLIDINE

Chemical Property:

Purity/Quality:: VEDACLIDINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of VEDACLIDINE

There total 8 articles about VEDACLIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1193-65-3
3-quinuclidinone hydrochloride

: 141593-42-2,141575-52-2
3-[4-(butylthio)-1,2,5-thiadiazol-3-yl]-1-azabicyclo-[2.2.2]octane

Guidance literature:: Multi-step reaction with 6 steps

1: Et₃N / 2 h / 80 °C

2: H₂ / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature

3: 1.) NaOMe, NaOEt, 2.) isoamyl nitrite, 3.) S₂Cl₂

4: H₂ / 5percentPd/C / ethanol / 760 Torr / Ambient temperature

5: NaHS*H₂O, K₂CO₃ / dimethylformamide / 2 h / Ambient temperature

6: dimethylformamide

With disulfur dichloride; sodium hydrogensulfide; hydrogen; sodium methylate; sodium ethanolate; potassium carbonate; triethylamine; isopentyl nitrite; palladium on activated charcoal; 5% Pd on active carbon; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm9602470

Reference yield:

: 141593-49-9
ethyl(1-azabicyclo[2.2.2]octan-3-ylidene)cyanoacetate

: 141593-42-2,141575-52-2
3-[4-(butylthio)-1,2,5-thiadiazol-3-yl]-1-azabicyclo-[2.2.2]octane

Guidance literature:: Multi-step reaction with 5 steps

1: H₂ / 10percent Pd/C / ethanol / 760 Torr / Ambient temperature

2: 1.) NaOMe, NaOEt, 2.) isoamyl nitrite, 3.) S₂Cl₂

3: H₂ / 5percentPd/C / ethanol / 760 Torr / Ambient temperature

4: NaHS*H₂O, K₂CO₃ / dimethylformamide / 2 h / Ambient temperature

5: dimethylformamide

With disulfur dichloride; sodium hydrogensulfide; hydrogen; sodium methylate; sodium ethanolate; potassium carbonate; isopentyl nitrite; palladium on activated charcoal; 5% Pd on active carbon; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm9602470

Reference yield:

: 141593-50-2
ethyl (1-azabicyclo[2.2.2]octan-3-yl)cyanoacetate

: 141593-42-2,141575-52-2
3-[4-(butylthio)-1,2,5-thiadiazol-3-yl]-1-azabicyclo-[2.2.2]octane

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaOMe, NaOEt, 2.) isoamyl nitrite, 3.) S₂Cl₂

2: H₂ / 5percentPd/C / ethanol / 760 Torr / Ambient temperature

3: NaHS*H₂O, K₂CO₃ / dimethylformamide / 2 h / Ambient temperature

4: dimethylformamide

With disulfur dichloride; sodium hydrogensulfide; hydrogen; sodium methylate; sodium ethanolate; potassium carbonate; isopentyl nitrite; 5% Pd on active carbon; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm9602470