2-AMino-cyclohex-1-enecarbonitrile

Base Information

• Chemical Name: 2-AMino-cyclohex-1-enecarbonitrile
• CAS No.: 15595-71-8
• Molecular Formula: C7H10 N2
• Molecular Weight: 122.17
• Hs Code.: 2926909090
• Mol file: 15595-71-8.mol

Synonyms:1-Amino-2-cyanocyclohex-1-ene;2-Amino-1-cyclohexene-1-carbonitrile; NSC 153146

Chemical Property of 2-AMino-cyclohex-1-enecarbonitrile

Chemical Property:

• Vapor Pressure: 0.00021mmHg at 25°C
• Melting Point: 94-95 °C
• Boiling Point: 326.9°Cat760mmHg
• PKA: 6.72±0.20(Predicted)
• Flash Point: 151.5°C
• PSA: 49.81000
• Density: 1.05g/cm³
• LogP: 1.99708

Purity/Quality:

98%min ^*data from raw suppliers

2-aminocyclohex-1-ene-1-carbonitrile ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-AMino-cyclohex-1-enecarbonitrile

There total 6 articles about 2-AMino-cyclohex-1-enecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

pimelonitrile (646-20-8) → 2-aminocyclohex-1-enecarbonitrile (15595-71-8)

Guidance literature:

With lithium N-ethyl-N-phenylamide; In diethyl ether; hexane; Heating;

DOI:10.1016/0040-4020(95)00394-N

Reference yield:

2-cyanocyclohexanone (4513-77-3) → 2-aminocyclohex-1-enecarbonitrile (15595-71-8)

Guidance literature:

With ammonium carbonate;

Reference yield:

2-amino-2-hydroxy-cyclohexanecarbonitrile (861316-16-7) → 2-aminocyclohex-1-enecarbonitrile (15595-71-8)

Guidance literature:

With water;

upstream raw materials:

2-cyanocyclohexanone

2-amino-2-hydroxy-cyclohexanecarbonitrile

pimelonitrile

water

Downstream raw materials:

2-Isocyanatocyclohex-1-encarbonsaeurenitril

9-phenyl-1,2,3,4,5,6,7,8-octahydro-acridine

2,6-bis(benzylidene)cyclohexanone

1-benzylidene-9-phenyl-1,2,3,4,5,6,7,8-octahydroacridine

Refernces

• 1、 Takaya, Hikaru,Naota, Takeshi,Murahashi, Shun-Ichi. "Iridium Hydride Complex Catalyzed Addition of Nitriles to Carbon-Nitrogen Triple Bonds of Nitriles". . p. 4244 - 4245. Retrieved 1998.
• 2、 Aradi, Klra,Novk, Zoltn. "Copper-catalyzed oxidative ring closure of ortho-cyanoanilides with hypervalent iodonium salts: Arylation-ring closure approach to iminobenzoxazines". supporting information. p. 371 - 376. Retrieved 2015/03/05.
• 3、 -. "INDOLE CARBOXAMIDE DERIVATIVES AND USES THEREOF". Page/Page column 34. . Retrieved 2014/03/26.