Phenyl[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester

Base Information

Chemical Name:Phenyl[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester
CAS No.:481-64-1
Molecular Formula:C20H16O6
Molecular Weight:352.343
Hs Code.:
Mol file:481-64-1.mol

Synonyms:(E)-methyl 2-(3-hydroxy-4-(4-methoxyphenyl)-5-oxofuran-2(5H)-ylidene)-2-phenylacetate;[3-Hydroxy-4-(4-methoxy-phenyl)-5-oxo-5H-furan-(2E)-ylidene]-phenyl-acetic acid methyl ester;Pinastrinsaeure;[(E)-3-hydroxy-4-(4-methoxy-phenyl)-5-oxo-5H-[2]furylidene]-phenyl-acetic acid methyl ester;methyl (E)-2-(3-hydroxy-4-(4-methoxyphenyl)-5-oxofuran-2(5H)-ylidene)-2-phenylacetate;methyl [3-hydroxy-4-(4-methoxyphenyl)-5-oxo-5H-furan-2-ylidene]phenylacetate;(E)-4-hydroxy-5-(α-methoxycarbonylbenzylidene)-3-(4-methoxyphenyl)furan-2(5H)-one;

Suppliers and Price of Phenyl[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of Phenyl[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester

Chemical Property:

Vapor Pressure:5.83E-15mmHg at 25°C
Boiling Point:594.1°Cat760mmHg
Flash Point:215.6°C
PSA：82.06000
Density:1.363g/cm³
LogP:3.10540

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Phenyl[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester

There total 10 articles about Phenyl[(2E)-3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-ylidene]acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: methyl 2-hydroxy-2-(3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-yl)-2-phenylacetate

: 481-64-1
(E)-4-hydroxy-5-(α-methoxycarbonylbenzylidene)-3-(4-methoxyphenyl)furan-2(5H)-one

Guidance literature:: methyl 2-hydroxy-2-(3-hydroxy-4-(4-methoxyphenyl)-5-oxo-2,5-dihydrofuran-2-yl)-2-phenylacetate; With pyridine; trifluoroacetic anhydride; In dichloromethane; at 0 - 20 ℃; Inert atmosphere;

In toluene; for 8h; Inert atmosphere; UV-irradiation;
DOI:10.1021/jo802038z

Reference yield: 81.0%

: 1158649-25-2
methyl (Z)-2-(3-hydroxy-4-(4-methoxyphenyl)-5-oxofuran-2(5H)-ylidene)-2-iodoacetate

: 24388-23-6
2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole

: 481-64-1
(E)-4-hydroxy-5-(α-methoxycarbonylbenzylidene)-3-(4-methoxyphenyl)furan-2(5H)-one

Guidance literature:: With bis(triphenylphosphine)palladium(II)-chloride; sodium carbonate; In tetrahydrofuran; water; for 2h; Inert atmosphere; Reflux;
DOI:10.1016/j.tetlet.2009.03.011

Reference yield: 71.0%

: methyl [3-benzyloxy-4-(4-methoxyphenyl)-5-oxo-5H-furan-2-ylidene]phenylacetate

: 481-64-1
(E)-4-hydroxy-5-(α-methoxycarbonylbenzylidene)-3-(4-methoxyphenyl)furan-2(5H)-one

Guidance literature:: With hydrogenchloride; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide; for 2.5h; under 760.051 Torr;
DOI:10.1016/j.tetlet.2007.07.094