2,4-Bis(benzyloxy)-6-(ethanesulfonyl)-5-nitropyrimidine

Base Information

Chemical Name:2,4-Bis(benzyloxy)-6-(ethanesulfonyl)-5-nitropyrimidine
CAS No.:94219-38-2
Molecular Formula:C20H19N3O6S
Molecular Weight:429.453
Hs Code.:
DSSTox Substance ID:DTXSID70566643
Wikidata:Q82452351

Synonyms:94219-38-2;2,4-Bis(benzyloxy)-6-(ethanesulfonyl)-5-nitropyrimidine;DTXSID70566643

Suppliers and Price of 2,4-Bis(benzyloxy)-6-(ethanesulfonyl)-5-nitropyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 2,4-Bis(benzyloxy)-6-(ethanesulfonyl)-5-nitropyrimidine

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:8
Exact Mass:429.09945651
Heavy Atom Count:30
Complexity:638

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCS(=O)(=O)C1=NC(=NC(=C1[N+](=O)[O-])OCC2=CC=CC=C2)OCC3=CC=CC=C3

Technology Process of 2,4-Bis(benzyloxy)-6-(ethanesulfonyl)-5-nitropyrimidine

There total 1 articles about 2,4-Bis(benzyloxy)-6-(ethanesulfonyl)-5-nitropyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-chloro-5-nitrouracil

: 20194-18-7
sodium phenyl-methanolate

: 811-51-8
sodium thioethylate

: 94219-38-2
4-(ethylsulfonyl)-5-nitro-2,6-bis(phenylmethoxy)pyrimidine

Guidance literature:: Multistep reaction;
DOI:10.1016/S0040-4039(01)81450-7

Reference yield: 90.0%

: 94219-38-2
4-(ethylsulfonyl)-5-nitro-2,6-bis(phenylmethoxy)pyrimidine

: 94779-73-4
2-(methylthio)ethyl α-(aminoacetyl)-6-bromo-2,3-dihydro-2-oxo-1H-indole-3-acetate hydrochloride

: 94779-74-5
2-(methylthio)ethyl 6-bromo-2,3-dihydro-α-<<<5-nitro-2,6-bis(phenylmethoxy)-4-pyrimidinyl>amino>acetyl>-2-oxo-1H-indole-3-acetate

Guidance literature:: With sodium hydrogencarbonate; In N,N-dimethyl-formamide; for 1h; Ambient temperature;
DOI:10.1016/S0040-4020(01)86989-1

Reference yield:

: 94219-38-2
4-(ethylsulfonyl)-5-nitro-2,6-bis(phenylmethoxy)pyrimidine

: 94190-16-6,94190-17-7
(8-Acetyl-2,4-bis-benzyloxy-5,6,7,8-tetrahydro-pteridin-6-yl)-[1-acetyl-2-oxo-1,2-dihydro-indol-(3E)-ylidene]-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: NaHCO₃ / dioxane; H₂O / 7 h / Ambient temperature

2: Zn/HCl / tetrahydrofuran

3: pyridine / 2 h / 80 °C

4: NaBH₃CN, 2N HCl / ethyl acetate

With hydrogenchloride; sodium cyanoborohydride; sodium hydrogencarbonate; zinc; In tetrahydrofuran; 1,4-dioxane; pyridine; water; ethyl acetate;
DOI:10.1016/S0040-4039(01)81450-7