5-(2-(Diethylamino)ethylamino)-8-hydroxy-6H-(1,2,3)triazolo(4,5-1-de)acridin-6-one

Base Information

Chemical Name:5-(2-(Diethylamino)ethylamino)-8-hydroxy-6H-(1,2,3)triazolo(4,5-1-de)acridin-6-one
CAS No.:128113-19-9
Molecular Formula:C₁₇H₁₇N₅O₂
Molecular Weight:323.354
Hs Code.:
NSC Number:645827
UNII:5VNA4LC5RU
DSSTox Substance ID:DTXSID30155810
Nikkaji Number:J347.587E
Pharos Ligand ID:MHAV1BQLJHCK
ChEMBL ID:CHEMBL95704
Mol file:128113-19-9.mol

Synonyms:5-(2-(diethylamino)ethylamino)-8-hydroxy-6H-(1,2,3)triazolo(4,5-1-de)acridin-6-one;C 1303;C-1303;C1303

Suppliers and Price of 5-(2-(Diethylamino)ethylamino)-8-hydroxy-6H-(1,2,3)triazolo(4,5-1-de)acridin-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 5-(2-(Diethylamino)ethylamino)-8-hydroxy-6H-(1,2,3)triazolo(4,5-1-de)acridin-6-one

Chemical Property:

Vapor Pressure:9.68E-15mmHg at 25°C
Boiling Point:594.7°Cat760mmHg
Flash Point:313.5°C
Density:1.46g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:323.13822480
Heavy Atom Count:24
Complexity:488

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)CCNC1=C2C3=C(C=C1)N=NN3C4=C(C2=O)C=C(C=C4)O

Technology Process of 5-(2-(Diethylamino)ethylamino)-8-hydroxy-6H-(1,2,3)triazolo(4,5-1-de)acridin-6-one

There total 3 articles about 5-(2-(Diethylamino)ethylamino)-8-hydroxy-6H-(1,2,3)triazolo(4,5-1-de)acridin-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 128113-28-0
5-chloro-8-hydroxy-6H-ν-triazolo<4,5,1-de>acridin-6-one

: 108-00-9
N,N-dimethylethylenediamine

: 128113-19-9
5-<2-(dimethylamino)ethylamino>-8-hydroxy-6H-<1,2,3>-triazolo<4,5,1-de>acridin-6-one

Guidance literature:: With N,N-dimethyl acetamide; In chloroform; acetone; at 60 ℃; for 4h;
DOI:10.1021/jm00172a028

Reference yield:

: 128113-24-6
4-Amino-1-chloro-7-hydroxy-10H-acridin-9-one

: 128113-19-9
5-<2-(dimethylamino)ethylamino>-8-hydroxy-6H-<1,2,3>-triazolo<4,5,1-de>acridin-6-one

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / conc. hydrochloric acid, NaNO₂ / H₂O / 4 h / Ambient temperature

2: 80 percent / N,N-dimethylacetamide (DMA) / acetone; CHCl₃ / 4 h / 60 °C

With hydrogenchloride; N,N-dimethyl acetamide; sodium nitrite; In chloroform; water; acetone;
DOI:10.1021/jm00172a028

Reference yield:

: 99009-49-1
1-chloro-7-hydroxy-4-nitro-9(10H)-acridinone

: 128113-19-9
5-<2-(dimethylamino)ethylamino>-8-hydroxy-6H-<1,2,3>-triazolo<4,5,1-de>acridin-6-one

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / SnCl₂*2H₂O, conc. hydrochloric acid / ethanol / 6 h / Heating

2: 90 percent / conc. hydrochloric acid, NaNO₂ / H₂O / 4 h / Ambient temperature

3: 80 percent / N,N-dimethylacetamide (DMA) / acetone; CHCl₃ / 4 h / 60 °C

With hydrogenchloride; N,N-dimethyl acetamide; tin(ll) chloride; sodium nitrite; In ethanol; chloroform; water; acetone;
DOI:10.1021/jm00172a028