2-(4-Methoxyphenyl)-1,3-diphenylprop-2-en-1-one

Base Information

Chemical Name:2-(4-Methoxyphenyl)-1,3-diphenylprop-2-en-1-one
CAS No.:94348-31-9
Molecular Formula:C22H18O2
Molecular Weight:314.384
Hs Code.:
DSSTox Substance ID:DTXSID40705901

Synonyms:94348-31-9;2-(4-Methoxyphenyl)-1,3-diphenylprop-2-en-1-one;DTXSID40705901

Suppliers and Price of 2-(4-Methoxyphenyl)-1,3-diphenylprop-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-Methoxyphenyl)-1,3-diphenylprop-2-en-1-one

Chemical Property:

XLogP3:5.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:314.130679813
Heavy Atom Count:24
Complexity:419

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(=CC2=CC=CC=C2)C(=O)C3=CC=CC=C3

Technology Process of 2-(4-Methoxyphenyl)-1,3-diphenylprop-2-en-1-one

There total 5 articles about 2-(4-Methoxyphenyl)-1,3-diphenylprop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

: (E)-2-(4-methoxyphenyl)-3-phenylacryloyl chloride

: 98-80-6
phenylboronic acid

: 94348-31-9
(E)-2-(4-methoxyphenyl)-1,3-diphenylprop-2-en-1-one

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; In toluene; at 80 ℃; for 4h; Inert atmosphere;
DOI:10.1016/j.tetlet.2014.12.093

Reference yield:

: 24845-40-7
2-(4-methoxyphenyl)acetophenone

: 100-52-7
benzaldehyde

: 94348-31-9
(E)-2-(4-methoxyphenyl)-1,3-diphenylprop-2-en-1-one

: 94348-32-0
(Z)-2-(4-Methoxy-phenyl)-1,3-diphenyl-propenone

Guidance literature:: With piperidine; acetic acid; In benzene; Heating;
DOI:10.1021/jm00382a019

Reference yield:

: 1694-22-0,6387-65-1,20432-25-1
(E)-2-(4-methoxyphenyl)-3-phenylacrylic acid

: 94348-31-9
(E)-2-(4-methoxyphenyl)-1,3-diphenylprop-2-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 0 - 20 °C

2: bis-triphenylphosphine-palladium(II) chloride; potassium phosphate / toluene / 4 h / 80 °C / Inert atmosphere

With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; toluene; 2: |Suzuki Coupling;
DOI:10.1016/j.tetlet.2014.12.093