2-{[(2,4-Dimethoxyphenyl)methyl]amino}-acetonitrile hydrochloride

Base Information

Chemical Name:2-{[(2,4-Dimethoxyphenyl)methyl]amino}-acetonitrile hydrochloride
CAS No.:94459-09-3
Molecular Formula:C11H14N2O2
Molecular Weight:206.244
Hs Code.:2926907090
Mol file:94459-09-3.mol

Synonyms:(2,4-Dimethoxy-benzylamino)-acetonitrile;[(2,4-dimethoxybenzyl)amino]acetonitrile;

Suppliers and Price of 2-{[(2,4-Dimethoxyphenyl)methyl]amino}-acetonitrile hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-{[(2,4-Dimethoxyphenyl)methyl]amino}acetonitrile hydrochloride
1 g
$ 800.00

SynQuest Laboratories
2-{[(2,4-Dimethoxyphenyl)methyl]amino}acetonitrile hydrochloride
500 mg
$ 592.00

Total 3 raw suppliers

Chemical Property of 2-{[(2,4-Dimethoxyphenyl)methyl]amino}-acetonitrile hydrochloride

Chemical Property:

PSA：54.28000
LogP:1.70788

Purity/Quality:: 2-{[(2,4-Dimethoxyphenyl)methyl]amino}acetonitrile hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-{[(2,4-Dimethoxyphenyl)methyl]amino}-acetonitrile hydrochloride

There total 1 articles about 2-{[(2,4-Dimethoxyphenyl)methyl]amino}-acetonitrile hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 20781-20-8
2,4-Dimethoxybenzylamine

: 590-17-0
cyanomethyl bromide

: 94459-09-3
<(2,4-dimethoxybenzyl)amino>acetonitrile

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 - 25 ℃; for 16h;

Reference yield:

: 25504-47-6
methyl (RS)-2-oxopiperidine-4-carboxylate

: 94459-09-3
<(2,4-dimethoxybenzyl)amino>acetonitrile

: 2-(2,4-dimethoxybenzyl)-2,7-diazaspiro[3.5]nonane-1,6-dione

Guidance literature:: methyl (RS)-2-oxopiperidine-4-carboxylate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 - -40 ℃; for 1h; Inert atmosphere;

<(2,4-dimethoxybenzyl)amino>acetonitrile; In tetrahydrofuran; at -78 - 0 ℃; for 3h; Inert atmosphere;

Reference yield:

: 94459-09-3
<(2,4-dimethoxybenzyl)amino>acetonitrile

: (R)-3-Amino-3-benzyl-1-(2,4-dimethoxy-benzyl)-azetidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: LHMDS / acetonitrile / -70 °C

1.2: acetonitrile / -70 - 20 °C

2.1: H₂ / Pd/C / methanol / 20 °C

With hydrogen; lithium hexamethyldisilazane; palladium on activated charcoal; In methanol; acetonitrile;
DOI:10.1016/j.bmcl.2006.10.047