4-Amino-3-chlorobenzenesulfonyl fluoride

Base Information

• Chemical Name: 4-Amino-3-chlorobenzenesulfonyl fluoride
• CAS No.: 1996-51-6
• Molecular Formula: C6H5 Cl F N O2 S
• Molecular Weight: 209.63
• Hs Code.: 2921499090
• NSC Number: 136586
• DSSTox Substance ID: DTXSID60300396
• Wikidata: Q82043412
• Mol file: 1996-51-6.mol

Synonyms:1996-51-6;4-Amino-3-chlorobenzenesulfonyl fluoride;4-amino-3-chlorobenzene-1-sulfonyl fluoride;Benzenesulfonyl fluoride, 4-amino-3-chloro-;3-Chloro-4-amino benzene sulphonylfluoride;NSC136586;4-Amino-3-chlorobenzenesulphonyl fluoride;starbld0000298;4-Amino-3-chloro-benzenesulfonyl fluoride;SCHEMBL5738131;2-chloro-4-fluorosulphonylaniline;DTXSID60300396;NSC-136586;SB78410;4-amino-3-chlorophenylsulfonyl fluoride;BS-53377;CS-0529694;FT-0617490;E84469;EN300-1581790;A814115;1,1,1,2,2,3,3,4,4,5,5,6,6-tridecafluoro-8-iododecane

Chemical Property of 4-Amino-3-chlorobenzenesulfonyl fluoride

Chemical Property:

• Vapor Pressure: 9.78E-05mmHg at 25°C
• Melting Point: 130°C
• Boiling Point: 305.8°Cat760mmHg
• Flash Point: 138.8°C
• PSA: 68.54000
• Density: 1.559g/cm³
• LogP: 3.24240
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 208.9713554
• Heavy Atom Count: 12
• Complexity: 251

Purity/Quality:

99% ^*data from raw suppliers

4-AMINO-3-CHLOROBENZENESULFONYL FLUORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C=C1S(=O)(=O)F)Cl)N

Technology Process of 4-Amino-3-chlorobenzenesulfonyl fluoride

There total 1 articles about 4-Amino-3-chlorobenzenesulfonyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-Chloro-4-amino benzene sulphonylfluoride (1996-51-6)

Guidance literature:

4-Nitro-3-chlor-benzolsulfonylfluorid, Hydrierung, Raney-Ni., A.;

Reference yield: 71.0%

3-Chloro-4-amino benzene sulphonylfluoride (1996-51-6) + isobutylamine (78-81-9) → 4-amino-3-chloro-N-isobutylbenzenesulfonamide (278179-04-7)

Guidance literature:

With pyridine; In acetonitrile; for 24h;

DOI:10.1021/jm0000923

Reference yield:

α-Acetoxyisobutyryl chloride (69798-63-6) + 3-Chloro-4-amino benzene sulphonylfluoride (1996-51-6) → N-(2-chloro-4-fluorosulphonylphenyl)-2-acetoxy-2-methylpropanamide

Guidance literature:

With pyridine; In dichloromethane; at 20 ℃; for 18h;

Downstream raw materials:

4-amino-3-chloro-N-(3,4,5-trimethoxy-benzyl)-benzenesulfonamide

4-amino-3-chloro-N-decyl-benzenesulfonamide

4-amino-3-chloro-N-isobutylbenzenesulfonamide

acetic acid 1-(2-chloro-4-isobutylsulfamoylphenylcarbamoyl)-1-methylethyl ester