alpha-L-lyxo-Hexopyranoside, methyl 3-amino-2,3,6-trideoxy-

Base Information

• Chemical Name: alpha-L-lyxo-Hexopyranoside, methyl 3-amino-2,3,6-trideoxy-
• CAS No.: 18977-92-9
• Molecular Formula: C₇H₁₅NO₃
• Molecular Weight: 161.201
• Hs Code.: 2932999099
• Nikkaji Number: J1.122.850J
• Mol file: 18977-92-9.mol

Synonyms:methyl 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexapyranoside;methyl daunosamine;methyldaunosamine

Chemical Property of alpha-L-lyxo-Hexopyranoside, methyl 3-amino-2,3,6-trideoxy-

Chemical Property:

• Vapor Pressure: 0.00124mmHg at 25°C
• Boiling Point: 265.7°Cat760mmHg
• Flash Point: 114.5°C
• PSA: 64.71000
• Density: 1.13g/cm³
• LogP: 0.15620
• XLogP3: -0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 161.10519334
• Heavy Atom Count: 11
• Complexity: 131

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C(C(CC(O1)OC)N)O
• Isomeric SMILES: C[C@H]1[C@H]([C@H](C[C@@H](O1)OC)N)O

Technology Process of alpha-L-lyxo-Hexopyranoside, methyl 3-amino-2,3,6-trideoxy-

There total 60 articles about alpha-L-lyxo-Hexopyranoside, methyl 3-amino-2,3,6-trideoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl 3-amino-3-N,4-O-carbonyl-2,3,6-trideoxy-α-L-lyxo-hexopyranoside (914378-72-6) → methyl α-L-daunosaminide (18977-92-9)

Guidance literature:

With barium hydroxide octahydrate; In water; at 125 ℃; for 1h;

DOI:10.1021/jo061167z

Reference yield: 92.0%

Methyl 3-azido-2,3,6-trideoxy-α-L-lyxo-hexopyranoside (18981-64-1,72002-52-9) → methyl α-L-daunosaminide (18977-92-9)

Guidance literature:

With hydrogen; platinum(IV) oxide; In methanol; Ambient temperature;

DOI:10.1021/jo00174a028

Reference yield: 88.0%

2,3,4,6-tetradeoxy-4',5'-dihydro-2'-trichloromethyl(methyl α-DL-lyxo-hexopyranosido)<3,4-d>oxazole (83803-06-9,116558-52-2,116558-53-3) → methyl α-DL-daunosaminide (18977-92-9,34598-18-0,51869-33-1,54623-23-3,63864-98-2,67693-33-8,67737-60-4,72402-68-7,76793-38-9,77398-20-0,78853-97-1,80483-20-1,80483-25-6,85439-73-2,85439-77-6,116429-70-0,116429-72-2,116836-60-3,131896-61-2)

Guidance literature:

With sodium hydroxide; In methanol; water; at 50 ℃; for 2h;

upstream raw materials:

Methyl N-methoxycarbonyl-L-daunosaminide

Methyl 3-azido-2,3,6-trideoxy-α-L-lyxo-hexopyranoside

Methyl 4-O-(trichloroacetimidoyl)-2,3,6-trideoxy-α-L-threo-hex-2-enopyranoside

methyl 3-amino-3-N,4-O-carbonyl-2,3,6-trideoxy-α-L-lyxo-hexopyranoside

Downstream raw materials:

methyl 3-acetamido-2,3,6-trideoxy-α-L-lyxo-hexopyranoside

N,O-diacetyl-α-daunosaminide

N,O-Diacetyl-L-daunosamine α-methylglycoside

N,O-Diacetyl-L-daunosamine β-methylglycoside