N-(tricyclo[3.3.1.1~3,7~]dec-1-yl)-3-(trimethylgermanyl)propanamide

Base Information

• Chemical Name: N-(tricyclo[3.3.1.1~3,7~]dec-1-yl)-3-(trimethylgermanyl)propanamide
• CAS No.: 112703-50-1
• Molecular Formula: C₁₆H₂₉GeNO
• Molecular Weight: 324.002
• Mol file: 112703-50-1.mol

Synonyms:

Chemical Property of N-(tricyclo[3.3.1.1~3,7~]dec-1-yl)-3-(trimethylgermanyl)propanamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(tricyclo[3.3.1.1~3,7~]dec-1-yl)-3-(trimethylgermanyl)propanamide

There total 2 articles about N-(tricyclo[3.3.1.1~3,7~]dec-1-yl)-3-(trimethylgermanyl)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

β-(trimethylgermyl)propionyl chloride (112703-54-5) + N-adamant-1-yl-N-trimethylsilylamine (36960-58-4) → N-(1-adamantyl)-3-(trimethylgermyl)propionamide (112703-50-1)

Guidance literature:

In further solvent(s); addn. of acid chloride in dichloroethane to Si-compound, temp. kept at <30°C, mixt. left for 2 h at 20°C; evapn.; elem. anal.;

Reference yield: 69.0%

β-(trimethylgermyl)propionyl chloride (112703-54-5) + 1-Adamantanamine (768-94-5) → N-(1-adamantyl)-3-(trimethylgermyl)propionamide (112703-50-1)

Guidance literature:

In further solvent(s); addn. of acid chloride in dichloroethane to amine in dichloroethane, temp. kept at <30°C, reacted for 3h, pptn.; ppt. filtered off, filtrate evapd.; elem. anal.;

Reference yield: 91.0%

hydrogenchloride (7647-01-0,15364-23-5) + N-(1-adamantyl)-3-(trimethylgermyl)propionamide (112703-50-1) → N-(1-adamantyl)-3-(trimethylgermyl)propionamide hydrochloride (112927-38-5)

Guidance literature:

In diethyl ether; dry HCl passed through soln. of Ge-compound at room temp. for 1 h, pptn.; ppt. filtered off; elem. anal.;

upstream raw materials:

β-(trimethylgermyl)propionyl chloride

1-Adamantanamine

N-adamant-1-yl-N-trimethylsilylamine

Downstream raw materials:

N-(1-adamantyl)-3-(trimethylgermyl)propionamide hydrochloride