2-Ethyl-3-hydroxy-6-methylpyridine

Base Information

Chemical Name:2-Ethyl-3-hydroxy-6-methylpyridine
CAS No.:2364-75-2
Deprecated CAS:123939-43-5
Molecular Formula:C8H11NO
Molecular Weight:137.181
Hs Code.:2933399090
European Community (EC) Number:680-170-6
UNII:V247P5H4E1
DSSTox Substance ID:DTXSID40178313
Nikkaji Number:J153.925F
Wikipedia:Emoxypine
Wikidata:Q4532982
ChEMBL ID:CHEMBL3338326
Mol file:2364-75-2.mol

Synonyms:2-ethyl-6-methyl-3-hydroxypyridine;2-ethyl-6-methyl-3-oxypyridine;6-methyl-2-ethyl-3-hydroxypyridine;6-methyl-2-ethyl-3-hydroxypyridine hydrochloride;6-methyl-2-ethyl-3-hydroxypyridine monohydrochloride;emoxipin;emoxipine;emoxypin;emoxypine;Epigid;hydroxypyridine-6

Suppliers and Price of 2-Ethyl-3-hydroxy-6-methylpyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Emoxipine
10g
$ 1165.00

TCI Chemical
2-Ethyl-3-hydroxy-6-methylpyridine
5G
$ 50.00

SynQuest Laboratories
2-Ethyl-3-hydroxy-6-methylpyridine
100 g
$ 204.00

SynQuest Laboratories
2-Ethyl-3-hydroxy-6-methylpyridine
10 g
$ 32.00

SynQuest Laboratories
2-Ethyl-3-hydroxy-6-methylpyridine
5 g
$ 20.00

Matrix Scientific
2-Ethyl-3-hydroxy-6-methylpyridine 95+%
1g
$ 15.00

Matrix Scientific
2-Ethyl-3-hydroxy-6-methylpyridine 95+%
10g
$ 225.00

Matrix Scientific
2-Ethyl-3-hydroxy-6-methylpyridine 95+%
5g
$ 34.00

Labseeker
2-Ethyl-3-hydroxy-6-methylpyridine 95
25g
$ 450.00

Crysdot
2-Ethyl-3-hydroxy-6-methylpyridine 95+%
100g
$ 151.00

Total 153 raw suppliers

Chemical Property of 2-Ethyl-3-hydroxy-6-methylpyridine

Chemical Property:

Vapor Pressure:0.0022mmHg at 25°C
Melting Point:136-138 °C
Refractive Index:1.536
Boiling Point:280.6 °C at 760 mmHg
PKA:10.59±0.10(Predicted)
Flash Point:123.5 °C
PSA：33.12000
Density:1.053 g/cm³
LogP:1.65800
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:137.084063974
Heavy Atom Count:10
Complexity:105

Purity/Quality:

99% ^*data from raw suppliers

Emoxipine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(C=CC(=N1)C)O
Uses An antidepressant agent. An antidepressant

Technology Process of 2-Ethyl-3-hydroxy-6-methylpyridine

There total 10 articles about 2-Ethyl-3-hydroxy-6-methylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.2%

: 10599-69-6
5-methyl-2-propionylfuran

: 2364-75-2
emoxypine

Guidance literature:: With ammonia; toluene-4-sulfonic acid; at 170 ℃; for 5h; under 10501.1 Torr; Temperature; Pressure; Autoclave;

Reference yield: 90.0%

: 1344663-48-4
2-ethyl-6-methylpyridin-3-amine

: 2364-75-2
emoxypine

Guidance literature:: With sulfuric acid; sodium nitrite; In water; at 0 ℃; Reflux;
DOI:10.1021/ol202597b

Reference yield:

: 21203-68-9
2-methyl-5-nitropyridine

: 2364-75-2
emoxypine

Guidance literature:: Multi-step reaction with 4 steps

1.1: carbamide peroxide; trifluoroacetic anhydride / dichloromethane / 0 - 20 °C

2.1: tetrahydrofuran / -60 °C / Inert atmosphere

2.2: -60 - 20 °C / Inert atmosphere

3.1: iron; acetic acid / 5 h / 110 °C

4.1: sulfuric acid; sodium nitrite / water / 0 °C / Reflux

With sulfuric acid; carbamide peroxide; iron; acetic acid; trifluoroacetic anhydride; sodium nitrite; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/ol202597b