Technology Process of L-Leucine, N-[N-[N-[N-(N-glycyl-L-valyl)-L-seryl]-L-phenylalanyl]-L-valyl]-
There total 12 articles about L-Leucine, N-[N-[N-[N-(N-glycyl-L-valyl)-L-seryl]-L-phenylalanyl]-L-valyl]- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium;
In
water; butan-1-ol;
for 4.5h;
DOI:10.1248/cpb.32.4608
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 85 percent / Et3N / acetonitrile / Ambient temperature
2: catalytic hydrogenation
3: 53.6 percent / DCC / acetonitrile / Ambient temperature
4: catalytic hydrogenation
5: 65.1 percent / dimethylformamide / 4 °C
6: 71.7 percent / anisole / trifluoroacetic acid / 2.5 h / Ambient temperature
7: 94 percent / hydrogen / Pd / H2O; butan-1-ol / 4.5 h
With
hydrogen; methoxybenzene; triethylamine; dicyclohexyl-carbodiimide;
palladium;
In
water; N,N-dimethyl-formamide; acetonitrile; trifluoroacetic acid; butan-1-ol;
DOI:10.1248/cpb.32.4608
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 83 percent / 80percent hydrazine hydrate / methanol / Ambient temperature
2: 7 N HCl, isoamylnitrite / dioxane
3: 65.1 percent / dimethylformamide / 4 °C
4: 71.7 percent / anisole / trifluoroacetic acid / 2.5 h / Ambient temperature
5: 94 percent / hydrogen / Pd / H2O; butan-1-ol / 4.5 h
With
hydrogenchloride; hydrogen; hydrazine hydrate; methoxybenzene; isopentyl nitrite;
palladium;
In
1,4-dioxane; methanol; water; N,N-dimethyl-formamide; trifluoroacetic acid; butan-1-ol;
DOI:10.1248/cpb.32.4608
