2-Isoindolinebutyramide, 1,3-dioxo-

Base Information

Chemical Name:2-Isoindolinebutyramide, 1,3-dioxo-
CAS No.:3459-33-4
Molecular Formula:C12H12N2O3
Molecular Weight:232.2353
Hs Code.:2925190090
DSSTox Substance ID:DTXSID30188148
Nikkaji Number:J68.619K
Wikidata:Q83059953
Mol file:3459-33-4.mol

Synonyms:4-Phthalimidobutyramide;1,3-Dioxo-2-isoindolinebutyramide;Phthalimide, N-(carbamoylpropyl)-;2-ISOINDOLINEBUTYRAMIDE, 1,3-DIOXO-;3459-33-4;BRN 0018270;2H-Isoindole-2-butanamide, 1,3-dihydro-1,3-dioxo-;Oprea1_386084;SCHEMBL5041554;DTXSID30188148;MFCD00709196;AKOS002964806;LS-84699;4-(1,3-dioxoisoindolin-2-yl) butanamide;4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)butanamide

Suppliers and Price of 2-Isoindolinebutyramide, 1,3-dioxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)BUTANAMIDE 95.00%
5MG
$ 505.74

Total 2 raw suppliers

Chemical Property of 2-Isoindolinebutyramide, 1,3-dioxo-

Chemical Property:

Vapor Pressure:2.48E-09mmHg at 25°C
Boiling Point:478.9°Cat760mmHg
Flash Point:243.4°C
PSA：81.46000
Density:1.334g/cm³
LogP:1.63570
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:232.08479225
Heavy Atom Count:17
Complexity:330

Purity/Quality:

95% ^*data from raw suppliers

4-(1,3-DIOXO-1,3-DIHYDRO-2H-ISOINDOL-2-YL)BUTANAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C2=O)CCCC(=O)N

Technology Process of 2-Isoindolinebutyramide, 1,3-dioxo-

There total 5 articles about 2-Isoindolinebutyramide, 1,3-dioxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 10314-06-4
4-phthalimidobutyryl chloride

: 3459-33-4
4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)butyramide

Guidance literature:: With ammonia; In dichloromethane; at 0 - 20 ℃;
DOI:10.1002/1521-4184(200110)334:10<323::AID-ARDP323>3.0.CO;2-O

Reference yield: 23.0%

: 3459-33-4
4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)butyramide

Guidance literature:

Reference yield:

: 85-44-9
phthalic anhydride

: 3459-33-4
4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)butyramide

Guidance literature:: Multi-step reaction with 3 steps

1: 82 percent / Et₃N / toluene / 2 h / Heating

2: SOCl₂ / 1 h / Heating

3: 85 percent / NH₃ / CH₂Cl₂ / 0 - 20 °C

With thionyl chloride; ammonia; triethylamine; In dichloromethane; toluene;
DOI:10.1002/1521-4184(200110)334:10<323::AID-ARDP323>3.0.CO;2-O