Technology Process of 1H-Pyrrole-2-carboxylic acid,
4-ethyl-3-methyl-5-[2-(3-methyl-1-oxo-2-butenyl)-1,3-dithian-2-yl]-,
phenylmethyl ester
There total 8 articles about 1H-Pyrrole-2-carboxylic acid,
4-ethyl-3-methyl-5-[2-(3-methyl-1-oxo-2-butenyl)-1,3-dithian-2-yl]-,
phenylmethyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium acetate;
In
tert-butyl alcohol;
for 6.5h;
Heating;
DOI:10.1039/P19840002725
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 73 percent / potassium acetate, methylamine hydrochloride, trimethylorthoformate / methanol / 1 h / Heating
2: 93 percent / sodium borohydride / dimethylformamide; methanol
3: 77.2 percent / diazabicyclononane / dimethylformamide / 16 h / 35 °C
4: 1.) potassium t-butoxide, 2.) titanium(III) chloride / 1.) THF, 25 min, 2.) 1 h
5: 76.2 percent / potassium acetate / 2-methyl-propan-2-ol / 6.5 h / Heating
With
sodium tetrahydroborate; diazabicyclononane; potassium tert-butylate; methylamine hydrochloride; potassium acetate; titanium(III) chloride; trimethyl orthoformate;
In
methanol; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1039/P19840002725
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 77.2 percent / diazabicyclononane / dimethylformamide / 16 h / 35 °C
2: 1.) potassium t-butoxide, 2.) titanium(III) chloride / 1.) THF, 25 min, 2.) 1 h
3: 76.2 percent / potassium acetate / 2-methyl-propan-2-ol / 6.5 h / Heating
With
diazabicyclononane; potassium tert-butylate; potassium acetate; titanium(III) chloride;
In
N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1039/P19840002725
