965-20-8

Usage

Molecular structure

Contains a phenylmethyl ester, a pyrrole ring, a carboxylic acid group at the 2-position, a formyl group at the 5-position, and an ethyl group and a methyl group attached to the pyrrole ring.

Unique structural features

The presence of both a pyrrole ring and a phenylmethyl ester structure contribute to its unique properties and potential applications in medicinal chemistry.

Research and pharmaceutical development

The compound is utilized in research and pharmaceutical development due to its potential applications in medicinal chemistry.

Variable properties and applications

The specific properties and applications of the compound may vary depending on the context and the specific uses for which it is employed.

Upstream product

• 103041-75-4 4-ethyl-5-bromomethyl-3-methyl-pyrrole-2-carboxylic acid benzyl ester 
• 51089-83-9 benzyl 4-ethyl-3-methyl-1H-pyrrole-2-carboxylate 
• 68-12-2 N,N-dimethyl-formamide 
• 2386-27-8 benzyl 4-acetyl-3,5-dimethylpyrrole-2-carboxylate 
• 5396-89-4 benzyl acetoacetate 
• 123-54-6 acetylacetone 
• 83089-91-2 benzyl 3-ethyl-2-iodo-4-methylpyrrole-5-carboxylate 
• 967-38-4 2-(benzyloxycarbonyl)-4-ethyl-3-methylpyrrole-5-carboxylic acid 
• 13219-63-1 5-dichloromethyl-4-ethyl-3-methyl-pyrrole-2-carboxylic acid benzyl ester 
• 1925-61-7 benzyl 4-ethyl-3,5-dimethylpyrrole-2-carboxylate 

Downstream Products

• 133864-97-8 C₅₂H₄₈N₆O₄ 
• 95305-40-1 benzyl 4-ethyl-3-methyl-5-(2-hydroxyimino-4-methylpentyl)pyrrole-2-carboxylate 
• 95305-40-1 benzyl 4-ethyl-3-methyl-5-(2-hydroxyimino-4-methylpentyl)pyrrole-2-carboxylate 
• 95305-31-0 benzyl 4-ethyl-5-(3,3-dimethyl-2-nitro-5-oxohexyl)-3-methylpyrrole-2-carboxylate 
• 95305-46-7 benzyl 4-ethyl-3-methyl-5-<2-(3-methyl-1-oxobut-2-enyl)-1,3-dithian-2-yl>pyrrole-2-carboxylate 
• 95305-35-4 benzyl 4-ethyl-3-methyl-5-(3-hydroxy-4-methyl-2-nitropentyl)pyrrole-2-carboxylate 
• 95305-32-1 5-(5-benzyloxycarbonyl-3-ethyl-4-methylpyrrol-2-ylmethyl)-3,4-dihydro-2,4,4-trimethylpyrrole 1-oxide 
• 95305-33-2 5-(5-benzyloxycarbonyl-3-ethyl-4-methylpyrrol-2-ylmethyl)-3,4-dihydro-2,4,4-trimethylpyrrole 
• 95305-37-6 benzyl 4-ethyl-3-methyl-5-(4-methyl-2-nitropent-3-enyl)pyrrole-2-carboxylate 
• 95305-38-7 benzyl 4-ethyl-3-methyl-5-(4-methyl-2-nitropent-2E-enyl)pyrrole-2-carboxylate 
• 95305-30-9 benzyl 4-ethyl-3-methyl-5-(2-nitroethyl)pyrrole-2-carboxylate 
• 95305-39-8 benzyl 4-ethyl-3-methyl-5-(4-methyl-2-oxopent-3-enyl)pyrrole-2-carboxylate 
• 1925-61-7 benzyl 4-ethyl-3,5-dimethylpyrrole-2-carboxylate 
• 98619-41-1 benzyl 5-<(E)-2-cyano-2-(methoxycarbonyl)ethenyl>-4-ethyl-3-methyl-2-pyrrolecarboxylate 

Relevant academic research and scientific papers

Steric control of mesocate and helicate formation: Bulky pyrrol-2-yl Schiff base complexes of Zn2+

Regioisomerism about a phenyl spacer alters the number of nuclei which participate in self-assembly with pyrrole/schiff base ditopic ligands. The bulky benzyl ester substituents favor formation of di- and tetranuclear (but not trinuclear) complexes. The r

Pyrrophens: Pyrrole-Based Hexadentate Ligands Tailor-Made for Uranyl (UO22+) Coordination and Molecular Recognition

Derivatives of a novel pyrrole-containing Schiff base ligand system (called "pyrrophen") are presented which feature substituted phenylene linkers (R1 = R2 = H (H2L1); R1 = R2 = CH3 (H2L2)) and a binding pocket modeled after macrocyclic species. These lig

A convenient synthetic route to the bacteriochlorin chromophore

The reactions of an A,C-divinylporphyrin with activated dienophiles yield stable bis Diels-Alder adducts absorbing light at wavelengths above 735 nm. This provides a convenient general route to bacteriochlorin-like chromophores.

REACTION ON SOLID SUPPORT PART V: THE MECHANISM OF OXIDATION OF α-METHYLPYRROLES TO α-FORMYLPYRROLES BY TALLIUM NITRATE ON CLAY

Evidence is presented to show that the clay-catalyzed thallium nitrate oxidation of α-methylpyrroles to α-formylpyrroles involves formation of an intermediate nitrate ester which subsequently undergoes elimination of nitrite.

5-Unsubstituted 2-Pyrrolecarboxaldehydes for Porphyrin Synthesis and the Cyanovinyl Protecting Group

(Cyanovinyl)pyrroles (13) derived from the Knoevenagel condensation of benzyl 5-formyl-2-pyrrolecarboxylates (12) with methyl cyanoacetate were employed in a facile sequence of four steps to produce, regioselectively, 5-unsubstituted 2-pyrrolecarboxaldehy

Stereochemical Studies on Porphyrin a: Assignment of the Absolute Configuration of a Model Porphyrin by Degradation

The synthesis is described of a porphyrin alcohol (22) which has a structure very similar to that of porphyrin a (2).The model porphyrin was resolved by separation of its camphanate esters.Ozonolysis of the 2-nitrobenzoate of each enantiomer in tritiated form gave a derivative of 2-hydroxypentadioic acid whose configuration was determined by dilution analysis.It is demonstrated that correlation of the stereochemistry of porphyrin a with that of the model (22) will be possible by means of the (1)H and (19)F n.m.r. spectra of the corresponding esters with (-)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid.

Novel Porphyrins from Copper(II)-Mediated Cyclizations of 1',8'-Dimethyl-a,c-biladiene Salts: Mechanism of the Cyclization Reaction

Copper(II)-mediated cyclizations of the 1',8'-dimethyl-a,c-biladiene 8 under various conditions afford the expected porphyrin 7, along with γ-methyl- (9), γ-(dialkylamino)- (10 and 11), 6-formyl- (12), and γ-formylporphyrins (13).Carbon-13-enriched a,c-bi

An Improved Preparation of 2-Pyrrolecarbaldehydes from 2-Methylpyrroles

Reaction of 2-methylpyrroles with lead(IV) acetate in chloroform affords 2-pyrrolecarbaldehydes with improved yields.Namely the yields of pyrrolecarbaldehydes with unsubstituted ring positions are increased efficiently.

REACTIONS ON SOLID SUPPORTS PART I: NOVEL PREPARATION OF α-FORMYL PYRROLES FROM α-METHYLPYRROLES BY OXIDATION WITH THALLIUM (III) NITRATE ON CLAY

Treatment of α-methylpyrroles with thallium (III) nitrate/Montmorillonite clay affords the corresponding α-formylpyrroles in excellent yields.