2-Allylaminopyridine

Base Information

• Chemical Name: 2-Allylaminopyridine
• CAS No.: 5866-28-4
• Molecular Formula: C8H10N2
• Molecular Weight: 134.181
• European Community (EC) Number: 632-568-6
• NSC Number: 92746
• DSSTox Substance ID: DTXSID30974200
• Nikkaji Number: J945.023H
• Wikidata: Q82958381
• Mol file: 5866-28-4.mol

Synonyms:2-allylaminopyridine;N-prop-2-enylpyridin-2-amine;N-Allyl-2-pyridinamine;5866-28-4;Pyridine, 2-propenylamino- (6CI);100377-15-9;n-(prop-2-en-1-yl)pyridin-2-amine;NSC92746;N-Allylpyridin-2-amine;Pyridine, 2-(allylamino)-;SCHEMBL1002291;DTXSID30974200;NSC-92746;AKOS004123552

Chemical Property of 2-Allylaminopyridine

Chemical Property:

• Vapor Pressure: 0.0475mmHg at 25°C
• Boiling Point: 236.4°Cat760mmHg
• Flash Point: 96.8°C
• Density: 1.03g/cm³
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 134.084398327
• Heavy Atom Count: 10
• Complexity: 101

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C=CCNC1=CC=CC=N1

Technology Process of 2-Allylaminopyridine

There total 9 articles about 2-Allylaminopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

pyridine N-oxide (694-59-7) + 1-amino-2-propene (107-11-9,30551-89-4) → 2-(prop-2-enylamino)pyridine (5866-28-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; In dichloromethane; at 25 ℃; for 15h;

DOI:10.1021/ol102301u

Reference yield: 73.0%

2-chloropyridine (109-09-1) + 1-amino-2-propene (107-11-9,30551-89-4) → 2-(prop-2-enylamino)pyridine (5866-28-4)

Guidance literature:

With 1,1'-bis-(diphenylphosphino)ferrocene; sodium t-butanolate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In tetrahydrofuran; at 80 ℃; for 3h;

DOI:10.1016/S0040-4039(97)10877-2

Reference yield: 73.0%

2,3-dihydrothiazolo<3,2-a>pyridinium bromide (1541-40-8) + 1-amino-2-propene (107-11-9,30551-89-4) → 2-(prop-2-enylamino)pyridine (5866-28-4)

Guidance literature:

In dimethyl sulfoxide; at 50 ℃; for 48h;

DOI:10.1016/j.tet.2008.09.010

upstream raw materials:

Natrium-Verbindung des [2]Pyridylamins

allyl bromide

2-chloropyridine

1-amino-2-propene

Downstream raw materials:

2-aminopyridine

(S)-N-(pyridin-2-yl)-1-amino-2-propanol

imidazo[1,2-a]pyridine-3-carbaldehyde

biphenyl