Technology Process of Pyridinium,
3-acetyl-1-[2-[2-[1-(methoxycarbonyl)ethenyl]-1-methyl-1H-indol-3-yl]eth
yl]-, iodide
There total 7 articles about Pyridinium,
3-acetyl-1-[2-[2-[1-(methoxycarbonyl)ethenyl]-1-methyl-1H-indol-3-yl]eth
yl]-, iodide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium iodide;
In
acetonitrile;
at 75 - 80 ℃;
for 54h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 58.2 g / sodium hydride / tetrahydrofuran / 1.) reflux, 5 min, 2.) room temperature, 0.5 h
2: 38.0 g / KOH, H2O / methanol / 1 h
3: 5.60 g / thionyl chloride / diethyl ether / 2 h / Ambient temperature
4: 56 percent / aluminium chloride / 0.5 h / 65 - 70 °C
5: 1.) n-butyl-lithium / 1.) hexane, THF, 5 min, 2.) THF, room temperature, 2 h
6: 86 percent / sodium iodide / acetonitrile / 54 h / 75 - 80 °C
With
potassium hydroxide; n-butyllithium; aluminium trichloride; thionyl chloride; water; sodium hydride; sodium iodide;
In
tetrahydrofuran; methanol; diethyl ether; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 55.3 g / AnalaR pyridine / 1 h / Ambient temperature
2: 58.2 g / sodium hydride / tetrahydrofuran / 1.) reflux, 5 min, 2.) room temperature, 0.5 h
3: 38.0 g / KOH, H2O / methanol / 1 h
4: 5.60 g / thionyl chloride / diethyl ether / 2 h / Ambient temperature
5: 56 percent / aluminium chloride / 0.5 h / 65 - 70 °C
6: 1.) n-butyl-lithium / 1.) hexane, THF, 5 min, 2.) THF, room temperature, 2 h
7: 86 percent / sodium iodide / acetonitrile / 54 h / 75 - 80 °C
With
pyridine; potassium hydroxide; n-butyllithium; aluminium trichloride; thionyl chloride; water; sodium hydride; sodium iodide;
In
tetrahydrofuran; methanol; diethyl ether; acetonitrile;
