3H-Diazirine, 3-bromo-3-[4-(trifluoromethyl)phenyl]-

Base Information

Chemical Name:3H-Diazirine, 3-bromo-3-[4-(trifluoromethyl)phenyl]-
CAS No.:95911-64-1
Molecular Formula:C8H4BrF3N2
Molecular Weight:265.032
Hs Code.:
DSSTox Substance ID:DTXSID00470522
Nikkaji Number:J2.347.732G
Mol file:95911-64-1.mol

Synonyms:95911-64-1;3-bromo-3-(4-(trifluoromethyl)phenyl)-3H-diazirine;3-bromo-3-[4-(trifluoromethyl)phenyl]-3H-diazirine;3H-Diazirine, 3-bromo-3-[4-(trifluoromethyl)phenyl]-;DTXSID00470522

Suppliers and Price of 3H-Diazirine, 3-bromo-3-[4-(trifluoromethyl)phenyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3H-Diazirine, 3-bromo-3-[4-(trifluoromethyl)phenyl]-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:263.95100
Heavy Atom Count:14
Complexity:250

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2(N=N2)Br)C(F)(F)F

Technology Process of 3H-Diazirine, 3-bromo-3-[4-(trifluoromethyl)phenyl]-

There total 4 articles about 3H-Diazirine, 3-bromo-3-[4-(trifluoromethyl)phenyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 898562-59-9
C₈H₄Cl₃F₃N₂

: 95911-64-1
3-(p-(trifluoromethyl)phenyl)diazirine

Guidance literature:: With lithium bromide; In acetonitrile; at 20 ℃; for 0.166667h;
DOI:10.1021/jo060341g

Reference yield: 19.0%

: 38980-96-0
4-(trifluoromethyl)benzimidamide hydrochloride

: 95911-64-1
3-(p-(trifluoromethyl)phenyl)diazirine

Guidance literature:: With sodium hypobromide; lithium bromide; In dimethyl sulfoxide; for 1h;
DOI:10.1021/ja00295a029

Reference yield:

: 455-18-5
4-CF₃C₆H₄CN

: 95911-64-1
3-(p-(trifluoromethyl)phenyl)diazirine

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / 1.) sodium methoxide; 2.) NH₄Cl / methanol / 25 °C / 1.) 48 h; 2.) 24 h

2: 19 percent / NaOBr, LiBr / dimethylsulfoxide / 1 h

With sodium hypobromide; sodium methylate; ammonium chloride; lithium bromide; In methanol; dimethyl sulfoxide;
DOI:10.1021/ja00295a029