5-(4-Methylphenyl)-1-phenylpyrazolidin-3-one

Base Information

Chemical Name:5-(4-Methylphenyl)-1-phenylpyrazolidin-3-one
CAS No.:95994-33-5
Molecular Formula:C16H16N2O
Molecular Weight:252.316
Hs Code.:
DSSTox Substance ID:DTXSID30545353
Mol file:95994-33-5.mol

Synonyms:95994-33-5;1-phenyl-5-(p-tolyl)pyrazolidin-3-one;5-(4-Methylphenyl)-1-phenylpyrazolidin-3-one;SCHEMBL10956322;DTXSID30545353

Suppliers and Price of 5-(4-Methylphenyl)-1-phenylpyrazolidin-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(4-Methylphenyl)-1-phenylpyrazolidin-3-one

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:252.126263138
Heavy Atom Count:19
Complexity:317

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2CC(=O)NN2C3=CC=CC=C3

Technology Process of 5-(4-Methylphenyl)-1-phenylpyrazolidin-3-one

There total 2 articles about 5-(4-Methylphenyl)-1-phenylpyrazolidin-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 7560-43-2,20754-20-5,50363-84-3
methyl 3-(4-methylphenyl)acrylate

: 100-63-0
phenylhydrazine

: 95994-33-5
1-phenyl-5-p-tolylpyrazolidin-3-one

Guidance literature:: methyl 3-(4-methylphenyl)acrylate; With sodium methylate; ethanolamine; In butan-1-ol; for 0.666667h; Reflux;

phenylhydrazine; In butan-1-ol; for 8h; Reflux;
DOI:10.1002/jhet.424

Reference yield: 63.0%

: 62427-24-1
3-bromo-3-(p-tolyl)acrylaldehyde

: 100-63-0
phenylhydrazine

: 1097651-66-5
2-phenyl-5-(p-tolyl)pyrazolidin-3-one

: 95994-33-5
1-phenyl-5-p-tolylpyrazolidin-3-one

Guidance literature:: With 2-mesityl-6,7-dihydro-5H-pyrrolo[2,1-c][1,2,4]triazol-2-ium tetrafluoroborate; triethylamine; In 1,2-dimethoxyethane; at 30 ℃; regioselective reaction; Schlenk technique; Inert atmosphere;
DOI:10.1039/c7ob02041d