Pyridazino(4,3-c)isoquinoline, 3-phenyl-6-(1-pyrrolidinyl)-

Base Information

Chemical Name:Pyridazino(4,3-c)isoquinoline, 3-phenyl-6-(1-pyrrolidinyl)-
CAS No.:96826-01-6
Molecular Formula:C21H18N4
Molecular Weight:326.39
Hs Code.:
ChEMBL ID:CHEMBL25258
DSSTox Substance ID:DTXSID50242579
Wikidata:Q83126364

Synonyms:BRN 5609401;Pyridazino(4,3-c)isoquinoline, 3-phenyl-6-(1-pyrrolidinyl)-;96826-01-6;3-Phenyl-6-(1-pyrrolidinyl)pyridazino(4,3-c)isoquinoline;3-phenyl-6-(1-pyrrolidinyl)pyridazino[4,3-c]isoquinoline;CHEMBL25258;SCHEMBL10736799;DTXSID50242579;FRXHUKCFBXGFBN-UHFFFAOYSA-N

Suppliers and Price of Pyridazino(4,3-c)isoquinoline, 3-phenyl-6-(1-pyrrolidinyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of Pyridazino(4,3-c)isoquinoline, 3-phenyl-6-(1-pyrrolidinyl)-

Chemical Property:

PSA：41.91000
LogP:4.51020
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:326.153146591
Heavy Atom Count:25
Complexity:443

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C2=NC3=CC(=NN=C3C4=CC=CC=C42)C5=CC=CC=C5

Technology Process of Pyridazino(4,3-c)isoquinoline, 3-phenyl-6-(1-pyrrolidinyl)-

There total 5 articles about Pyridazino(4,3-c)isoquinoline, 3-phenyl-6-(1-pyrrolidinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 123-75-1
pyrrolidine

: 96825-78-4
6-Chloro-3-phenyl-pyridazino-[4,3-c]-isoquinoline

: 96826-01-6
3-phenyl-6-(1-pyrrolidinyl)pyridazino-[4,3-c]isoquinoline

Guidance literature:: In 1,2-dimethoxyethane; at 120 - 140 ℃; for 8h; Heating;
DOI:10.1021/jm00147a034

Reference yield:

: 123-75-1
pyrrolidine

: 96826-00-5
3-Phenyl-pyridazino-[4,3-c]isoquinoline

: 96826-01-6
3-phenyl-6-(1-pyrrolidinyl)pyridazino-[4,3-c]isoquinoline

Guidance literature:: In 1,2-dimethoxyethane;

Reference yield:

: 96825-74-0
3-phenyl-pyridazino [4,3-c]isoquinolin-6-(5H)-one

: 96826-01-6
3-phenyl-6-(1-pyrrolidinyl)pyridazino-[4,3-c]isoquinoline

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / phosphorus pentachloride, phosphorus oxychloride / 3.5 h / Heating

2: 85 percent / 1,2-dimethoxy-ethane / 8 h / 120 - 140 °C / Heating

With phosphorus pentachloride; trichlorophosphate; In 1,2-dimethoxyethane;
DOI:10.1021/jm00147a034