Benzene, 1,1'-oxybis[4-methoxy-

Base Information

• Chemical Name: Benzene, 1,1'-oxybis[4-methoxy-
• CAS No.: 1655-74-9
• Molecular Formula: C14H14 O3
• Molecular Weight: 230.263
• Hs Code.: 2909309090
• DSSTox Substance ID: DTXSID7061853
• Nikkaji Number: J421.586I
• Wikidata: Q81989712
• Mol file: 1655-74-9.mol

Synonyms:1655-74-9;Benzene, 1,1'-oxybis[4-methoxy-;1-methoxy-4-(4-methoxyphenoxy)benzene;bis(4-methoxyphenyl) ether;Benzene, 1,1'-oxybis(4-methoxy-;4-methoxyphenyl ether;dimethoxydiphenyl ether;SCHEMBL83811;Levothyroxine Sodium Impurity 6;DTXSID7061853;BCP34167;Bis(4-methoxyphenyl) ether;6-methyl-2-(4-methylphenyl)imidazo[1,2-a]-pyridine-3-acetic acid (zolpidic acid)

Chemical Property of Benzene, 1,1'-oxybis[4-methoxy-

Chemical Property:

• Vapor Pressure: 0.000226mmHg at 25°C
• Melting Point: 102 °C
• Boiling Point: 335.9°Cat760mmHg
• Flash Point: 112.8°C
• PSA: 27.69000
• Density: 1.106g/cm³
• LogP: 3.49610
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 230.094294304
• Heavy Atom Count: 17
• Complexity: 182

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)OC2=CC=C(C=C2)OC

Technology Process of Benzene, 1,1'-oxybis[4-methoxy-

There total 22 articles about Benzene, 1,1'-oxybis[4-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

para-iodoanisole (696-62-8) + 4-methoxy-phenol (150-76-5) → bis(4-methoxyphenyl) ether (1655-74-9)

Guidance literature:

With copper(I) oxide; caesium carbonate; imidazole-4-carboxylic acid; In acetonitrile; at 80 ℃; for 24h;

DOI:10.1016/j.tetlet.2011.10.149

Reference yield: 95.0%

1-bromo-4-methoxy-benzene (104-92-7) + 4-methoxy-phenol (150-76-5) → bis(4-methoxyphenyl) ether (1655-74-9)

Guidance literature:

With caesium carbonate; acetylacetone; In N,N-dimethyl-formamide; at 130 ℃; for 4h; Inert atmosphere;

DOI:10.1002/cctc.201801111

Reference yield: 94.0%

4-methoxyphenylboronic acid (5720-07-0) → bis(4-methoxyphenyl) ether (1655-74-9)

Guidance literature:

With copper diacetate; water; triethylamine; In dichloromethane; acetonitrile; at 25 ℃; for 6h;

DOI:10.1016/S0040-4039(03)01776-3

upstream raw materials:

1-bromo-4-methoxy-benzene

potassium p-methoxyphenolate

4,4'-dihydroxydiphenyl ether

dimethyl sulfate

Downstream raw materials:

1,1,4,4-tetramethoxycyclohexa-2,5-diene

4-methoxy-phenol

N-phenyl-2-cyclohexylamine

methoxybenzene

Refernces

• 1、 Liu, Fu,Wei, Zhongbo,Wang, Liansheng,Wang, Zunyao. "Synthesis, experimental and theoretical investigation of molecular structure, IR, Raman spectra and 1H NMR analyses of 4,4′-dihydroxydiphenyl ether and 4,4′-oxybis(1-methoxybenzene)". . p. 285 - 294. Retrieved 2013.
• 2、 -. "Aromatic ether compound or the sulfhydryl compound". Paragraph 0072; 0074; 0078; 0109. . Retrieved 2021/11/19.
• 3、 Eslami, Mohammad,Jarahiyan, Atefeh,Moghaddam, Firouz Matloubi,Pourjavadi, Ali. "A novel magnetic polyacrylonotrile-based palladium Core?Shell complex: A highly efficientcatalyst for Synthesis of Diaryl ethers". . . Retrieved 2020/04/15.