3,4-Bis(4-chlorophenyl)hexanedioic acid

Base Information

• Chemical Name: 3,4-Bis(4-chlorophenyl)hexanedioic acid
• CAS No.: 1772-53-8
• Molecular Formula: C18H16Cl2O4
• Molecular Weight: 367.2232
• NSC Number: 77733
• DSSTox Substance ID: DTXSID30291747
• Mol file: 1772-53-8.mol

Synonyms:1772-53-8;3,4-bis(4-chlorophenyl)hexanedioic acid;NSC77733;DTXSID30291747;NSC-77733

Chemical Property of 3,4-Bis(4-chlorophenyl)hexanedioic acid

Chemical Property:

• Vapor Pressure: 1.44E-10mmHg at 25°C
• Boiling Point: 493.8°Cat760mmHg
• Flash Point: 252.4°C
• Density: 1.392g/cm³
• XLogP3: 4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 7
• Exact Mass: 366.0425644
• Heavy Atom Count: 24
• Complexity: 387

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(CC(=O)O)C(CC(=O)O)C2=CC=C(C=C2)Cl)Cl

Technology Process of 3,4-Bis(4-chlorophenyl)hexanedioic acid

There total 4 articles about 3,4-Bis(4-chlorophenyl)hexanedioic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

meso-3,4-diphenyl-adipic acid (65610-01-7) → meso-3,4-bis-(4-chloro-phenyl)-adipic acid (1772-53-8)

Guidance literature:

With chlorine; iron; acetic acid;

DOI:10.1002/hlca.19490320509

Reference yield:

racem.-3,4-diphenyl-adipic acid (25347-44-8,65610-00-6,65610-01-7,108391-56-6,108391-57-7) → d,l-3,4-Bis-<4-chlorphenyl>-adipinsaeure (1772-53-8)

Guidance literature:

DOI:10.1002/hlca.19490320509

Reference yield:

meso-3,4-diphenyl-adipic acid (65610-01-7) + chlorine (7782-50-5) + acetic acid (64-19-7,77671-22-8) → meso-3,4-bis-(4-chloro-phenyl)-adipic acid (1772-53-8)

Guidance literature:

DOI:10.1002/hlca.19490320509

upstream raw materials:

meso-3,4-diphenyl-adipic acid

chlorine

acetic acid

racem.-3,4-diphenyl-adipic acid